You mean Edith?
https://en.wikipedia.org/wiki/Edith_Wilson
From October 1919 to the end of Woodrow Wilson's term on March 4, 1921, Edith, acting in the role of First Lady and shadow steward, decided who and which communications and matters of state were important enough to bring to the bedridden president.[40]
Everyone draws this parallel, but that was before there were nuclear weapons.
Six minutes.
From the time a launch is detected, the NCA has SIX MINUTES to initiate authorization to access the football, select target packages (or approve the recommended target packages) and authorize the release of nuclear weapons. That includes finding POTUS, setting up the football, and having the right people in the room.