The overturning of Roe wasn’t the issue. It rightfully returned it to the States.
But then Miss Lindsey opened her pie-hole and floated the Federal Abortion Ban, and that was all she wrote!
Yes, it was rightfully returned to the states. But that meant state politics became way more important to the pro-abortion crowd. Previously, an anti-abortion Republican running for state office could easily say his or her personal views on abortion were irrelevant because states had no power over the abortion issue.
Graham's advantages in SC are that his opponent is always a Dem, and the GOP-e machine. He even got reelected when he was the image of GOP senate amnesty aspirations.