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“Magneto” Protein: Genetically Engineered To Control Brains And Behavior
technocracy.news ^ | June 17, 2021 | Mo Costandi via The Guardian

Posted on 06/20/2021 4:23:42 PM PDT by PetroniusMaximus

This is potentially the most dangerous and dystopian development in genetic modification in history. “The researchers inserted the Magneto DNA sequence into the genome of a virus”. The DNA behavior is then triggered by magnetic fields or radio waves. ⁃ TN Editor

Researchers in the United States have developed a new method for controlling the brain circuits associated with complex animal behaviours, using genetic engineering to create a magnetised protein that activates specific groups of nerve cells from a distance.

Understanding how the brain generates behaviour is one of the ultimate goals of neuroscience – and one of its most difficult questions. In recent years, researchers have developed a number of methods that enable them to remotely control specified groups of neurons and to probe the workings of neuronal circuits.

The most powerful of these is a method called optogenetics, which enables researchers to switch populations of related neurons on or off on a millisecond-by-millisecond timescale with pulses of laser light. Another recently developed method, called chemogenetics, uses engineered proteins that are activated by designer drugs and can be targeted to specific cell types.

Although powerful, both of these methods have drawbacks. Optogenetics is invasive, requiring insertion of optical fibres that deliver the light pulses into the brain and, furthermore, the extent to which the light penetrates the dense brain tissue is severely limited. Chemogenetic approaches overcome both of these limitations, but typically induce biochemical reactions that take several seconds to activate nerve cells.

The new technique, developed in Ali Güler’s lab at the University of Virginia in Charlottesville, and described in an advance online publication in the journal Nature Neuroscience, is not only non-invasive, but can also activate neurons rapidly and reversibly.

Several earlier studies have shown that nerve cell proteins which are activated by heat and mechanical pressure can be genetically engineered so that they become sensitive to radio waves and magnetic fields, by attaching them to an iron-storing protein called ferritin, or to inorganic paramagnetic particles. These methods represent an important advance – they have, for example, already been used to regulate blood glucose levels in mice – but involve multiple components which have to be introduced separately.

The new technique builds on this earlier work, and is based on a protein called TRPV4, which is sensitive to both temperature and stretching forces. These stimuli open its central pore, allowing electrical current to flow through the cell membrane; this evokes nervous impulses that travel into the spinal cord and then up to the brain.

Güler and his colleagues reasoned that magnetic torque (or rotating) forces might activate TRPV4 by tugging open its central pore, and so they used genetic engineering to fuse the protein to the paramagnetic region of ferritin, together with short DNA sequences that signal cells to transport proteins to the nerve cell membrane and insert them into it.

When they introduced this genetic construct into human embryonic kidney cells growing in Petri dishes, the cells synthesized the ‘Magneto’ protein and inserted it into their membrane. Application of a magnetic field activated the engineered TRPV1 protein, as evidenced by transient increases in calcium ion concentration within the cells, which were detected with a fluorescence microscope.

Next, the researchers inserted the Magneto DNA sequence into the genome of a virus, together with the gene encoding green fluorescent protein, and regulatory DNA sequences that cause the construct to be expressed only in specified types of neurons. They then injected the virus into the brains of mice, targeting the entorhinal cortex, and dissected the animals’ brains to identify the cells that emitted green fluorescence. Using microelectrodes, they then showed that applying a magnetic field to the brain slices activated Magneto so that the cells produce nervous impulses.

To determine whether Magneto can be used to manipulate neuronal activity in live animals, they injected Magneto into zebrafish larvae, targeting neurons in the trunk and tail that normally control an escape response. They then placed the zebrafish larvae into a specially-built magnetised aquarium, and found that exposure to a magnetic field induced coiling manouvres similar to those that occur during the escape response. (This experiment involved a total of nine zebrafish larvae, and subsequent analyses revealed that each larva contained about 5 neurons expressing Magneto.)

Read full story here… http://www.theguardian.com/science/neurophilosophy/2016/mar/24/magneto-remotely-controls-brain-and-behaviour


TOPICS: Culture/Society; News/Current Events
KEYWORDS: bloggers; chat; copyrightviolation; genes; magneto
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1 posted on 06/20/2021 4:23:42 PM PDT by PetroniusMaximus
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To: PetroniusMaximus

Tin foil hats to become fashionable and rational.


2 posted on 06/20/2021 4:26:40 PM PDT by arthurus ( covfefe.\)
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To: PetroniusMaximus

https://youtu.be/gHz_7e7yluM


3 posted on 06/20/2021 4:28:03 PM PDT by rfp1234 (Comitia asinorum et rhinocerum delenda sunt.)
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To: PetroniusMaximus

I’ve been demonstrating this for over 20 years and explaining the neuroscience behind how it works.

They don’t understand their own discovery.


4 posted on 06/20/2021 4:32:45 PM PDT by tired&retired (Blessings )
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To: arthurus

“Tin foil hats to become fashionable and rational.”

Tinfoil hat disabled. The voices really are coming from inside your head!


5 posted on 06/20/2021 4:33:49 PM PDT by SaxxonWoods (Any comment might be sarcasm, or not. It depends. Often I'm not sure either.)
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To: PetroniusMaximus

Switch it one way and you love liberals while reeling in horror at Donald Trump.

Nice to have leading up to Election Day—and sure to cause bizarre medical problems that can’t be traced—especially when it just takes five neurons to make you have a horrifying recoil.


6 posted on 06/20/2021 4:35:36 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: arthurus

Tin Foil hat’s
with Glasses and
Ear Plugs!
.
Beam me Up,
Scotty!


7 posted on 06/20/2021 4:39:18 PM PDT by Big Red Badger (Be Still and Know that I Am God. Rev 19)
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To: PetroniusMaximus

Early efforts that will become more advanced in short order.

Those who eventually take the Mark of the Beast may find that they will have chosen before even being asked.

Never take these “solutions” the government offers / demands.


8 posted on 06/20/2021 4:39:47 PM PDT by Rurudyne (Standup Philosopher)
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To: PetroniusMaximus

And this is useful for WHAT PURPOSE?
NO MORE!
No more m-RNA vaccines.
No more messing with human cell protein production and messing with human genetic receptors or the human genome!
Period.
These experiments must be defunded NOW.
NO MORE taxpayer dollars going to this sacrilegious bullshit!


9 posted on 06/20/2021 4:44:46 PM PDT by doc maverick
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To: arthurus

“Tin foil hats to become fashionable and rational.”

I take it you’re against prophylactic measures ?


10 posted on 06/20/2021 4:45:11 PM PDT by A strike (Barr to Gitmo, Roberts to Florence supermax, HerrDoktor FauxiGates to TerreHaute)
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To: PetroniusMaximus

They’ve overcomplicated it.

My solution: Virus that inserts the genes for Williams-Beuren syndrome. The genetics that make dogs friendly and eager to please.

Imagine a world full of people with happy puppy dog attitudes.


11 posted on 06/20/2021 4:47:27 PM PDT by DannyTN
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To: tired&retired

I knew a guy in college who said that he had managed to create a circuit that could transmit a soliton waveform, which could be looped back through the circuit. It didn’t interface with nerves or anything and he claimed his ambition was to make droids.


12 posted on 06/20/2021 4:53:10 PM PDT by Rurudyne (Standup Philosopher)
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To: PetroniusMaximus

Magnets sticking to Covid vaccine sites...


13 posted on 06/20/2021 4:53:16 PM PDT by Openurmind (The ultimate test of a moral society is the kind of world it leaves to its children. ~ D. Bonhoeffer)
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To: PetroniusMaximus

5G?


14 posted on 06/20/2021 4:53:19 PM PDT by Neverlift (When someone says "you just can't make this stuff up" odds are good, somebody did.)
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To: doc maverick
These experiments must be defunded NOW.

NO! We need more trials and tests to prove safety. These tests cannot be ran until the human trials are over. It is inhumane (and against PETA standards) to run these tests on mice/rats at this time. It's just too dangerous.

15 posted on 06/20/2021 4:58:50 PM PDT by BipolarBob (Who is John Galt and is he vaccinated?)
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To: rfp1234

That song was the first thing that popped into my head when I read the story title.
Great song.


16 posted on 06/20/2021 5:01:48 PM PDT by dznutz
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To: Rurudyne

Now that makes sense.


17 posted on 06/20/2021 5:05:09 PM PDT by bigbob
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To: DannyTN

Puppies are extremely easy to lead and to frighten.


18 posted on 06/20/2021 5:11:51 PM PDT by lee martell
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To: tired&retired

That’s nothing. I programmed them to make that discovery and be happy about it.


19 posted on 06/20/2021 5:20:50 PM PDT by Cvengr ( Adversity in life & death is inevitable; Stress is optional through faith in Christ.)
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To: PetroniusMaximus

Nice.


20 posted on 06/20/2021 5:23:52 PM PDT by fruser1
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