That was a big one for me. As the head of the republican party 43 defending himself bled over on us and could very easily have cost us the election in 2008. Even though we had the worst candidate ever McQueeg.
Along the line of thinking that a butterfly flapping his wings can cause a hurricane on the other side of the world...
If McCain would have won, we may be just entering Obama’s second term today. And of course, no Trump.