Twelve Monkeys is a movie that you have to watch....rewind....and watch a second time. Too many things involved in the plot...red herrings I’d call them....and by the end you really start to ask yourself about the premise of a disease beyond control.
I would strongly encourage you to go and read Daniel DeFoe’s 1722 novel A Journal of the Plague Year (downloadable on Amazon with their e-reader and free). It will walk you through the 1665/66 period of London and the effects of the plague. I should say...it is a fictional account but DeFoe really leads you through the various issues that confronted society, and how people just laid up boundaries and refuse people passage through their community by the mid-point.
Two other books about infectious disease - Barbara Tuchman’s A Distant Mirror about the 14th century. She’s something of a lib but very well written. And The Ghost Map about the 1850 cholera epidemic in London. Written by Steven Johnson. My SIL’s brother is the pathologist for the biggest hospital system in my metro area and this is one of his favorite books. He’s a bit odd but so am I.
I used to have an old book I bought back around 1962. THE PLAGUE AND THE FIRE. A history of those plague years. A terrible time to be alive.