Amish lethal microencephaly is one defect:
http://www.genome.gov/10004977
Sketch on p. 3, MRI on p. 4:
http://www3.interscience.wiley.com/cgi-bin/fulltext/94517067/PDFSTART
This center is smack dab in the Middle of Amish and Mennonite country. Visited once when I was in H.S. Saw some horrific things there. Babies..children..... and they didn’t show us the worst cases. They showed us the best. The things that burn in your brain.
dang, looks like a hobbit.