Shatter upon impact .50 cal round fired from a helicopter at the engine compartment of the car from above would do the trick. Such a round would penetrate the hood, shatter when it hits the engine block, but the fragmentation would cut up the radiator, hoses, belts and other soft plastic/rubber components. The engine area would start to leak and smoke and eventually the engine would overheat and seize up. Would be hell of a paperwork writeup for insurance purposes for the owner.
Rumor is the police are working on developing a remote control device which tells all cars nearby that have an onboard computer to shutdown and lock their doors.