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To: Know your rights
Delta-9 THC is burned up quickly, but 11-hydroxy-tetrahydrocannabinol and 11-nor-9-carboxy-delta-9-tetrahydrocannabinol linger for a while. There are more psychoactives in cannabis than just D-9.

There is a body of literature that contradicts your opinion, some of which I post below. If you are correct, and you may be, there must be an effort to refute the erroneous conclusions in the literature today.

A physician, or for that matter, a lawmaker, will be influenced by a peered journal than by a citizen that claims, no matter how sincerely, "but everyone knows..."

That's why I have been talking about conducting new research, specifically to look at medical use.

Do you have references to back up your point, which I think is, Delta 9 THC and other psychoactive compounds leave the body quickly, and the metabolites have no psychoactive potential- right? That's important because many papers state differently.

....................
http://www.psychiatrictimes.com/p020261.html

(this one differentiates)

The fact that 40% of subjects who had used marijuana regularly for an average of 22 years did not report experiencing severe withdrawal symptoms during abstinence might suggest that physical dependence on marijuana is not as strong as that observed with other drugs of abuse. This may be due, at least in part, to the long half-life of THC. However, many subjects reported that when trying to remain abstinent in the past, the presence of withdrawal symptoms had played an important role in their relapse. Thus, alleviation of abstinence symptoms may contribute to the maintenance of daily marijuana use in chronic users.
................
http://science.howstuffworks.com/marijuana4.htm

(does not differentiate between isomers)

The initial effects created by the THC in marijuana wear off after an hour or two, but the chemicals stay in your body for much longer. The terminal half-life of THC is from about 20 hours to 10 days, depending on the amount and potency of the marijuana used. This means that if you take one milligram of THC that has a half-life of 20 hours, you will still have 0.031 mg of THC in your body more than four days later. The longer the half-life, the longer the THC lingers in your body.

.......................
http://www.idmu.co.uk/drugtestcan.htm

(does not differentiate between types of THC)

2.1 Pharmacokinetics is the study of the time course of how drugs are distributed in the body, how long the effects last and how such effects relate to drug tests.

2.2 The major problem with measurement of metabolites is the very long detection times, owing the the rapid deposition of cannabinoids in inert fatty tissue following administration. Johannson et al[3] reported that total amount of THC metabolites and the levels of delta THC-acid could be followed up to 25 days after abstinence using EMIT cannabinoid assay and HPLC.

2.3 The residual level of THC in the bloodstream occurs when THC is released from the adipose (fatty) tissues, where it is deposited shortly after smoking. THC is also converted to its inert acid form within minutes of ingestion[4]. The half-life of THC in fatty tissue is approximately 8 days[5][6]. There is little evidence that clearance rates for THC differ significantly between naive and experienced cannabis users.
145 posted on 02/26/2006 6:55:33 PM PST by DBrow
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To: DBrow
Do NOT confuse MrLeRoy with the facts. He hates that.
158 posted on 02/27/2006 7:13:24 AM PST by robertpaulsen
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To: DBrow; robertpaulsen
"The positive results of a urine screen cannot be used to prove intoxication or impaired performance. Inert drug metabolites may appear in urine for several days, even weeks (depending on the drug), without being related impairment." - Walsh & Hawks, Employee Drug Screening, National Institute on Drug Abuse (NIDA), at 4 (1986).
211 posted on 02/28/2006 6:59:31 AM PST by Know your rights (The modern enlightened liberal doesn't care what you believe as long as you don't really believe it.)
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