de·fen·es·trate Audio pronunciation of "defenestrate" ( P ) Pronunciation Key (d-fn-strt)
tr.v. de·fen·es·trat·ed, de·fen·es·trat·ing, de·fen·es·trates
To throw out of a window.
In my personal framework of logic, defenestrate would mean "to render windowless," like unto defoliate. To throw out from (through) a window would be to "exfenestrate," a word not recognized by my Webster's, more's the pity.