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.40 S & W??!! For wimps!

A real he-man's (or she-woman's, in today's society) round is the classic .45 ACP. 230 grains of jacketed hollowpoints, such as Federal Hydra-Shoks do just fine.

With the lethality of the 40 being about 90% of the 45, but a magazine carrying 20%+ more rounds, a mag full of 40 is more lethal than a mag full of 45.

Unless we are talking about single shot defense pistols. ;-)

In my experience if ya have been raised exposed to trauma from contact sports, fights and ass whuppins from siblings and friends in play or pissin matches then your bodies ability to stand up to multiple wounds from any handgun round is high.

If you lived a protected life from such "exposure" where ya panic over a paper cut then you'll drop from a .22 rimfire round. I have been places where victims had never seen a TV show or Movie and didn't know they were supposed to fall down and die when shot.

The best chance one has in a handgun fight IMO is to make the fastest and quickest hits on his / her agressor with a modern hollowpoint projectile that has the speed and velocity to expell it's energy inside of a body cavity vs entry and exit hole and do such with as large a diameter "permanent wound channel" as possible be it a 40 short and wimpy or a nothing but 45 ACP !

Just my opinion.....Stay Safe !