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Posted on 08/07/2026 12:18:17 PM PDT by nickcarraway
For the first time ever, scientists have used artificial intelligence to design complete viral genomes that were physically synthesized and turned into 16 new functional viruses capable of replicating. The work was published in Science, one of the world’s most prominent scientific journals. Disturbingly, the study’s senior author, Brian L. Hie, who conceived, designed, and supervised the research disclosed funding from the Gates Foundation.
This was not a computer simulation. Researchers generated hundreds of AI-designed viral genomes, physically manufactured the DNA, assembled the genomes, introduced them into susceptible E. coli, and recovered 16 functional bacteriophages that successfully propagated. The viruses infected bacteria, suppressed bacterial growth, produced progeny, and were grown into working viral stocks. The study represents the first generative design of complete genomes that were synthesized and experimentally shown to function as viable viruses.
The scientists used Evo 1 and Evo 2, genomic large language models that operate essentially like LLMs for DNA. Instead of predicting the next word in a sentence, they predict the next nucleotide—A, C, G, or T. In other words, scientists are now using the same basic generative-AI paradigm behind systems such as ChatGPT to write entire viral genetic blueprints. Those digital sequences can then be converted into physical DNA and ultimately into functioning biological entities.
The resulting viruses were not simply carbon copies of a known phage. The successful AI-designed genomes contained 67 to 392 nucleotide changes relative to their closest known natural relatives, and 13 contained mutations that could not be identified in known natural sequences.
These particular viruses were bacteriophages that infect bacteria, not humans, and human-infecting viruses were excluded from the relevant training data. That fact does not make the underlying capability harmless. The dangerous precedent is the demonstration that an AI model can generate a complete viral genome, that genome can be commercially synthesized, and the resulting genetic material can produce a virus capable of replication. The barrier separating digital AI output from an operational biological agent has now been crossed.
The Gates Foundation funding attached to the senior scientist behind this project raises major concerns given that they also funded permanent quantum-dot microneedle patch “vaccines” that function as biological vaccine passports.
Moreover, the Gates Foundation previously gave $9.5 million to UW-Madison and principal investigator Yoshihiro Kawaoka to modify H5N1 viruses to preferentially recognize human-type receptors and transmit efficiently in mammals.
Bioterrorists no longer need to imagine a future in which AI can design pathogens from genetic code — the foundational capability has now been revealed in a major scientific journal. AI viral genome design technology should be halted before it falls into the hands of bioterrorists or other criminal actors.
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Wear a mask. A really big one.
Oh boy! If he makes viruses as good as his software the yippee /s
Gates has to be the whimpiest looking Bond villian, but probaby the most dangerous one.
How can this ghoul continue to roam the earth?
Make all who might be tempted fear to engage in such research.
Yeah, if you can breathe through it, a virus can pass through it.
Nothing is natural anymore, just synthetic.
“The viruses infected bacteria, suppressed bacterial growth”
So like antibiotics
Hold Gates financially liable for any issues.
He did tell us that COVID-1984 was just a test and the next one would be REALLY bad.
Never happen. And if we ever have Nuremburg II in the future, Gates will be the coward who takes the cyanide capsule before facing judgement.
Windows is the virus.
This could be a path to curing cancer.
But it’s unlikely to be used for that.
He does look wimpy and has a most punchable-looking face, but he sure has that telltale evil glint in his eyes.
Do you know how much they make for chemotherapy?
I do see the reference to Madison (U. Wisconsin), for previous Gates research.
“Gates Foundation Funds First-Ever Creation of 16 Synthetic Viruses Using AI”. Billy, I wish you would work on your OS, it’s a piece of shit.
See the villain in the 3rd Johnny English comedy flick (Rowan Atkinson), its Gates!
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