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Modified RNA has a direct effect on DNA
phys.org ^ | JANUARY 29, 2020 | by Eyrun Thune, University of Oslo

Posted on 02/17/2021 1:02:43 PM PST by RomanSoldier19

An article titled "m6A RNA modification as a new player in R-loop regulation," by the Dynamic Gene Regulation research group led by Arne Klungland at IMB, was published in the January edition of Nature Genetics.

Following a new collaboration between UiO and research groups in Nottingham and Oxford, it has now been revealed that RNA has a direct effect on DNA stability, according to Professor Klungland's research.

He believes the discovery will provide the health service with an important tool, since many studies have shown that the regulation of modifications to RNA is important for the development of cancer.

If genes that are important for the chemical compound 6-methyladenine are completely removed, this results in neurodegeneration in both mice and humans.

(Excerpt) Read more at phys.org ...


TOPICS: News/Current Events
KEYWORDS: bvitamins; cancer; cancerresearch; epigenetics; genetics; ivermection; mrna; rna; vaccine
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1 posted on 02/17/2021 1:02:43 PM PST by RomanSoldier19
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To: RomanSoldier19

It’s called epigenetics.

I see a problem with these posts from molecular biologically illiterate. It is the same as the liberals and their insane use of “the science” when they have no idea what they are talking about.


2 posted on 02/17/2021 1:06:57 PM PST by ifinnegan (Any saying " Democrats kill babies and harvest their organs to sell)
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To: RomanSoldier19

Russian rulette


3 posted on 02/17/2021 1:09:04 PM PST by patriot torch (Ashlie Babbitt-say her name)
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To: Fred Nerks

Ping to momre good news for alternate thgeaputics re: Covid 10

The only vax I would even consider at this point is Johnson & Johnson, a non RNA based medicine.


4 posted on 02/17/2021 1:12:38 PM PST by Candor7 ((Obama Fascism:http://www.americanthinker.com/2009/05/barack_obama_the_quintessentia_1.html) )
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To: RomanSoldier19

February 17, 2021
Head of Tokyo Medical Association recommends use of Ivermectin for Coronavirus patients and their caregivers
By Thomas Lifson

The cheap, generic drug Ivermectin, widely used against parasites, doesn’t seem to have a lot of friends in the American medical or journalistic establishments when it comes to treating Coronavirus. It’s been widely used overseas as a treatment for and prophylactic against Coronavirus, and is being prescribed for off-label use by some physicians in the US. But in CDC Guidelines issued last week, the official body noted that:

…Ivermectin has been widely used and is generally well tolerated [but] Ivermectin is not approved by the FDA for the treatment of any viral infection.

The CDC went on to state:
Reports from in vitro studies suggest that ivermectin acts by inhibiting the host importin alpha/beta-1 nuclear transport proteins, which are part of a key intracellular transport process that viruses hijack to enhance infection by suppressing the host’s antiviral response.4,5 In addition, ivermectin docking may interfere with the attachment of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein to the human cell membrane.6 Ivermectin is thought to be a host-directed agent, which may be the basis for its broad-spectrum activity in vitro against the viruses that cause dengue, Zika, HIV, and yellow fever.4,7-9 Despite this in vitro activity, no clinical trials have reported a clinical benefit for ivermectin in patients with these viruses. Some studies of ivermectin have also reported potential anti-inflammatory properties, which have been postulated to be beneficial in people with COVID-19.10-12

Some observational cohorts and clinical trials have evaluated the use of ivermectin for the prevention and treatment of COVID-19. Data from some of these studies can be found in Table 2c.

But the CDC refused to take a position on use of the drug against the current pandemic-causing virus:
There are insufficient data for the COVID-19 Treatment Guidelines Panel (the Panel) to recommend either for or against the use of ivermectin for the treatment of COVID-19. Results from adequately powered, well-designed, and well-conducted clinical trials are needed to provide more specific, evidence-based guidance on the role of ivermectin in the treatment of COVID-19.

But in Japan, the country where Ivermectin was invented and merited a Nobel Prize in \Medicine and Physiology for its creator, Professor Satoshi Omura, a very important member of the medical establishment has come out recommending Ivermectin for use on patients with Coronavirus, as a therapy, and for their caregivers.

The Nihon Keizai Shimbun (Japan’s version of the Wall Street Journal) reports:
At a press conference on the 9th, the chairman of the Tokyo Medical Association, Haruo Ozaki, recommended the emergency use of drugs, mainly to lessen the severity of home caregivers in order to respond to the spread of the new coronavirus infection. He emphasized that antiparasitic drugs such as “ivermectin” should be administered to corona-infected persons, saying that they have been shown to be effective in preventing aggravation of the condition overseas.

In addition to ivermectin, he called for the government to approve the use of the steroidal anti-inflammatory drug dexamethasone. Mr. Ozaki said, “(Both) have few side effects. I would like the government to consider so that treatment can be performed at the level of a family doctor.”
Both ivermectin and dexamethasone are prescribed domestically. However, it has not been approved as a treatment for corona. [Google Translate, slightly corrected by author]

The news last week that Ivermectin finally is going to get a rigorous study of its effectiveness against Coronavirus is a highly positive development. Because there is no big money to be made off of a generic drug, there’s no momentum for such studies in this country. Ivermectin is already so widely used that we have an excellent level of knowledge of its few downsides.

Alas, the same cannot be said of the Warp Speed vaccines currently being administered to tens of millions, worldwide


5 posted on 02/17/2021 1:12:51 PM PST by saintgermaine (THE TIME TRAVELLER )
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To: ifinnegan

6 posted on 02/17/2021 1:12:55 PM PST by RomanSoldier19 (Game over, man! Game over! ; : rem ad triarios redisse is)
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To: RomanSoldier19

In case anyone is wondering, what the linked article is discussing (modified RNA) has absolutely NOTHING to do with the mRNA (messenger RNA) employed in current COVID-19 vaccines.


7 posted on 02/17/2021 1:13:16 PM PST by House Atreides
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To: RomanSoldier19

One chance modification could lead to the elimination of the human race.


8 posted on 02/17/2021 1:14:44 PM PST by Revel
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To: saintgermaine

*


9 posted on 02/17/2021 1:15:28 PM PST by griswold3
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To: Revel

10 posted on 02/17/2021 1:16:30 PM PST by RomanSoldier19 (Game over, man! Game over! ; : rem ad triarios redisse is)
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To: RomanSoldier19

Does this have implications for the current vaccines?

Do we have the tools to detect mRNA modifications. And if so, can we modify them back to normal.


11 posted on 02/17/2021 1:18:09 PM PST by DannyTN
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To: House Atreides

“In case anyone is wondering, what the linked article is discussing (modified RNA) has absolutely NOTHING to do with the mRNA (messenger RNA) employed in current COVID-19 vaccines.”

No it doesn’t.

It’s akin to the leftists use of “follow the science”.

The idea that introducing RNA sequences in to the body may have unforeseen epigenetics consequences is a legitimate concern.

This article has nothing to do with knowing that.

Is the vaccine RNA adenosine methylated at the amino group?


12 posted on 02/17/2021 1:23:17 PM PST by ifinnegan (Any saying " Democrats kill babies and harvest their organs to sell)
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To: House Atreides
Re: "the linked article...has absolutely NOTHING to do with the mRNA...COVID-19 vaccines."

Thanks for clearing that up.

Even after reading it, I was not sure what point was being made.

13 posted on 02/17/2021 1:27:49 PM PST by zeestephen
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To: RomanSoldier19

mRNA bump for later...


14 posted on 02/17/2021 1:32:09 PM PST by indthkr
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To: griswold3

Thank you for telling me. Given a choice I would take IVERMECTION anytime over one of these quick concocted shots. Not to mention hat there are other ways and means to ease the effects of this virus, should you catch it, especially when taken in advance. Needless to say IVERMECTIN is cheap and no money can be made, same old story.


15 posted on 02/17/2021 1:33:00 PM PST by saintgermaine (THE TIME TRAVELLER )
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To: ifinnegan

“It’s called epigenetics.”

I agree.

And one of the greatest epigenetic influences is consciousness.

That’s how placebos work.


16 posted on 02/17/2021 1:39:09 PM PST by tired&retired (Blessings )
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To: saintgermaine

Excellent post on Ivermectin.

My apple flavored paste works just fine. And I don’t have worms. LOL..


17 posted on 02/17/2021 1:41:57 PM PST by tired&retired (Blessings )
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To: House Atreides

House Atreides wrote: “In case anyone is wondering, what the linked article is discussing (modified RNA) has absolutely NOTHING to do with the mRNA (messenger RNA) employed in current COVID-19 vaccines.”

No doubt. But I predict that within five days another freeper will post or link to this article as proof positive that the mRNA vaccines cause cancer.


18 posted on 02/17/2021 1:43:18 PM PST by DugwayDuke (Most prefer experts who only say things they agree with.)
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To: RomanSoldier19

I was all set to write a screenplay titled “The Great Die-Off.” Seven years after mass distribution of an experimental vaccine...
But hey, if no one’s going to be around to read it, maybe I’ll go back to calligraphy.


19 posted on 02/17/2021 1:44:38 PM PST by Buttons12 ( )
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To: ifinnegan

“Is the vaccine RNA adenosine methylated at the amino group?”

You must have read Randy Jirtle’s research here at Duke from back in 2003.

Amazing what a few B vitamins can do to epigenetically change a genetic predisposition to diabetes, obesity and cancer through methylation.


20 posted on 02/17/2021 1:48:15 PM PST by tired&retired (Blessings )
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