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Two different cases of PrEP failure despite high adherence underline that such events are rare, but should not be ignored
AIDS Map ^ | 4 September 2020 | Gus Cairns

Posted on 09/21/2020 11:41:13 AM PDT by fwdude

Two reports of HIV infection occurring despite apparent adequate adherence to PrEP, confirmed by drug level testing, are the first reliably documented cases to be published in peer-reviewed journals since 2018.

The most recent case was reported by Dr Matthew Spinelli in Clinical Infectious Diseases. It concerns a 44-year-old gay man in Texas and appears not to be due to poor adherence, but to infection with an HIV virus with an unusual combination of resistance mutations. Two characteristics of the case make it hard to argue against this being a genuine case of PrEP breakthrough. Firstly, samples of blood and hair confirm that he had had good adherence to PrEP in the two to three months leading up to his infection. Secondly, a pattern of HIV and viral load testing showed this was an acute infection that probably only occurred a few weeks at most before he reported symptoms. Notably, his initial positive HIV test was interpreted as a 'false positive' because his adherence appeared to be so good.

(Excerpt) Read more at aidsmap.com ...


TOPICS: Culture/Society; News/Current Events
KEYWORDS: aids; buttigieg; hiv; homosexualagenda; mayorpete; petebuttigieg; prep
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The tangled web sodomites weave can’t be mitigated by science or medicine. If you insist on jumping off cliffs, you’re going to fall hard.
1 posted on 09/21/2020 11:41:13 AM PDT by fwdude
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To: fwdude

Where 2 cases are identified, hundreds more are likely. And the way the sodomite community “networks,” this strain will likely spread nationwide in no time.

Time to quarantine?


2 posted on 09/21/2020 11:42:20 AM PDT by fwdude (Pass up too many hills to die on, and you will eventually fall off the edge of the world.)
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To: fwdude

Another virus Fauci failed to solve.


3 posted on 09/21/2020 11:44:26 AM PDT by Buckeye McFrog (Patrick Henry would have been an anti-vaxxer.)
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To: fwdude

Fecal sex has consequences.


4 posted on 09/21/2020 11:45:17 AM PDT by BenLurkin (The above is not a statement of fact. It is either opinion or satire. Or both.)
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To: fwdude
I am told to wear a mask even though I am not infected with anything that a mask could prevent from spreading.

But these guys who actually have a deadly infection are having sex with no condoms in sight and that is ok.

Yeah.

I have sound logical reasons for not wearing a mask but this kind of thing would make me go mask free just because.

5 posted on 09/21/2020 11:49:14 AM PDT by Harmless Teddy Bear (And lead us not into hysteria, but deliver us from the handwashers. Amen!)
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To: BenLurkin

PrEP was supposed to be the “silver bullet” that fags could use to ward off the gay disease. What will they try next? Abstinence? Hahahahaha!!!!


6 posted on 09/21/2020 11:50:06 AM PDT by fwdude (Pass up too many hills to die on, and you will eventually fall off the edge of the world.)
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To: fwdude

From the article

“The second, contrasting case was published earlier in the year but is reported here for the purposes of comparison. The 24-year-old gay man was on a clinical trial of PrEP that was comparing the efficacy of daily versus event-driven ‘2-1-1’ PrEP. He reported receptive anal sex, often involving chemsex drugs. He was screened for HIV and started PrEP in September 2018 and at this point was found to have, and was treated for, syphilis, gonorrhoea in the throat, and rectal chlamydia.”


7 posted on 09/21/2020 11:50:42 AM PDT by FewsOrange
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To: FewsOrange

I’m going to throw up. And I don’t throw up easily.


8 posted on 09/21/2020 11:51:55 AM PDT by fwdude (Pass up too many hills to die on, and you will eventually fall off the edge of the world.)
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To: fwdude
”Time to quarantine”?

Where would the masks go?
9 posted on 09/21/2020 11:54:16 AM PDT by LIConFem (I will no longer accept the things I cannot change. it's time to change the things I cannot accept)
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To: fwdude

My thought, exactly.


10 posted on 09/21/2020 11:57:11 AM PDT by Jane Long (Praise God, from whom ALL blessings flow.)
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To: Harmless Teddy Bear

Note that the queer hookup apps haven’t been shut down the way churches have.


11 posted on 09/21/2020 11:59:26 AM PDT by fwdude (Pass up too many hills to die on, and you will eventually fall off the edge of the world.)
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To: fwdude

oh, those awful commercials come to mind. Diseased flamers.


12 posted on 09/21/2020 12:06:12 PM PDT by ronniesgal (Q. why did the chicken cross the road? A. It's Trumps fault and you're a racist!)
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To: ronniesgal

What commercials? Without t.v., I’ve missed them, thankfully.


13 posted on 09/21/2020 12:17:29 PM PDT by fwdude (Pass up too many hills to die on, and you will eventually fall off the edge of the world.)
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To: fwdude

A completely preventable disease. It’s a pity they don’t stop the behavior that causes it. These meds just enable them to keep spreading it to more people for longer.


14 posted on 09/21/2020 12:20:36 PM PDT by Trillian
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To: fwdude

The Texas case looks like it might be a legitimate PrEP failure but the Hong Kong case probably wasn’t when you look at the details. I recall a French case recently mentioned on FR shows high degrees of drug resistance.


15 posted on 09/21/2020 12:24:06 PM PDT by newzjunkey (Vote Giant Meteor in 2020)
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To: fwdude

Lucky dog!!! I like some TV shows and we get inundated with homo love commercials. Blech.


16 posted on 09/21/2020 12:27:56 PM PDT by ronniesgal (Q. why did the chicken cross the road? A. It's Trumps fault and you're a racist!)
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To: fwdude

OK; Not being a FAGGOT/HOMO, just what the hell is PrEP?

Serious question, never heard of this PrEP before.


17 posted on 09/21/2020 12:36:01 PM PDT by 5th MEB (Progressives in the open; --- FIRE FOR EFFECT!!)
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To: FewsOrange

Oh God, that is vomit inducing.


18 posted on 09/21/2020 12:41:38 PM PDT by Trillian
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To: fwdude

Quarantine like in the fist wave of HIV.

Back in the eighties. Instead of quarantine they knocked off
a generation of hemophiliacs with tainted blood.


19 posted on 09/21/2020 12:45:28 PM PDT by wita (Always and forever, under oath in defence of Life, Liberty and the pursuit of Happiness.)
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To: 5th MEB

I didn’t know either so I looked it up:
“PrEP means Pre-Exposure Prophylaxis, and it’s the use of anti-HIV medications to keep HIV negative people from becoming infected”


20 posted on 09/21/2020 12:50:54 PM PDT by antidemoncrat (Biden's)
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