I favor the .45 m’self.
I stepped on a wolverine a while back... Before that was done, that wolverine took 4 of the 6 that Colt had in it (missed with 2) and was still coming - I finally beat it to death with a stump. That particular adventure is when I started carrying a carbine whenever I was in the woods...
Pistols are fine and all, but they aren't as effective a defense as one might think.
I favor the .45 mself
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Partial to the .357 beneath my left shoulder, and the 9mm behind my right hip, and the .380 Auto on my left ankle; none of them interfere with my running abilities; and I likely have the right tool for the job......though metal detectors are tough.