Madison opposed "popular opinion" as a claim of authority for any federal power not explicitly granted by the States and enumerated in the Constitution.
And, then, are you saying that my stating that the laws we’ve had on illegal drugs have reflected the popular opinion of the majority is contrary to what Madison wanted? I don’t think you mean to say Madison favored illegal drugs (though I know there are people on FReeRepublic who might say that), but are you saying he didn’t favor laws reflecting the values of the public in a self-governing nation?