As it stands, the entire population has been innoculated at some point in time.....except for illegals. And it’s one of those diseases where isolation works.
No one born since the late 60’s has, in fact, been vaccinated against smallpox unless they traveled overseas. They stopped even that vaccination in the 70’s IIRC. I’m in my mid 40’s and i’m the only one in my age group locally that has the smallpox scar. We traveled overseas when I was a wee babe.