Probably not telling you anything you don't know, but governments have actually fallen on pipeline issues. There was a huge pipeline debate in Canada in the mid 1950's over the route of a gas pipeline that was to bring Alberta gas to eastern Canada. Anyway the government of the day invoked cloture over the pipeline debate and that act basically caused the government to fall.
Three postscripts, lots of irony. There was a huge debate over the route of the pipeline, the shortest route ran through the USA, which needed US regulatory approval. Also, the builders (hated American "interests") needed a government loan to build the pipeline. Finally, the Canadian politician in charge of the bill was C.D. Howe, born and raised in Massachusetts, an American. How ironic is this?
Anyway, the line got built, the loans got paid off and C.D. Howe was defeated in his own riding. You might want to look him up on Wiki, he was very important in the war effort and is credited with the growth of manufacturing in Canada in the mid 20th century.
One final irony, today the C.D. Howe Institute is the leading Canadian conservative think tank. C.D. Howe, a businessman, and American by birth, was a member of the liberal party of Canada.