Despite the fact that they act to the contrary, I don't think Iran is stupid enough to go to war with the U.S. simply because we eliminated their chance to get nuclear weapons... I would expect brinkmanship and a LOT of international heat, but no war...
We actually have no way to eliminate their ability to obtain anything. After the fall or the Soviet block alot of ordinance including nuclear materials fell into the hands of the black market. US intelligence has known that for some time. We can only hope they don’t develope the technology to put any of those materials to use. Sanctions can only try to stop countries like Iran from implementing not from obtaining. That is a scary thought. Before we came along years ago none of the people of these countries were much more advanced than the camels they were riding we developed their oil production everything. They would be nothing if it had not been for the good old (evil) United States. I remember the first Gulf war with Irac when Suddam was firing Russian scud missiles at Israel we watched it on tv, what constitutes a weapon of mass destruction? Of course to discredit Bush they say nothing was found but how many years did Irac have to move those weapons? And how many times have we heard the truth? Israel has no liberals or a liberal media to whitewash what we hear. If they want to blow Iran off the face of the earth they have my support. Sounds like a darn good plan to me.
If that is too complicated for you, our side will be starting it, not Iran. It won't be up to Iran whether there is a war. Iran is going to barrel straight ahead getting nuclear weapons regardless. The only question is whether anyone will have the balls to stop them.