I am noting that the physical ramifications are so significant that they merit special mention in the Bible. I won't disagree that there are spiritual ramifications to female homosexuality, but they are more akin to alcoholism than to male homosexuality.
It isn't hard to think that even in those days, sexual diseases were well known, so the virgin bride wasn't just for ego and jealosy reasons, it was to protect from getting them and it's spread.
Woman diseases therefore would be thought spread woman to woman, or from whoredom. Also, the topic around Deut 22 is about chasity and faithfullness to the spouse. It stands to reason that this cross dressing verse also refers to homosexual behavior, rather than something off topic.