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Does it 'do' anything in the manifold? Or is it something we carry around like a baby in a gov't-approved car seat?

LOLOLOL! Thanks for the chuckle!

Yes, it manifests in the four dimensional block of space/time. How it manifests has a great deal to do with the levels of soul and spirit which I briefly discussed above with bvw. Some of the types:

Indwelling of the Spirit of God - for those who have this indwelling (born again Christians) - they are become a new person altogether, heavenly minded, Jesus centered, altruistic, etc. (Romans 8, I Cor 2, John 15-17, etc.) Note that Abraham, Moses, David, etc. were also led of the Spirit.

Neshama - the descendants of Adamic man have the breath of God. This may be interpreted as "ears to hear" (John 10) - a predisposition to seek God, look for answers to the deep questions, e.g. "what is the meaning of life?"

Ruach - (AFAIK) the intent of the man, willfulness - also a pivot whether to be Godly minded or earthy minded.

Nephesh - the material will of living organisms. The will to live, the want to live, the struggle to survive. Also, motherly instincts, etc.

IOW, the soul/spirit is a gradient all of which has a manifestation in four dimensional space/time - a sense of Truth, morality, willfulness, qualia (likes/dislikes, pain/pleasure).

And in turn, these intents cause the cascade of successful communication (information) in the molecular machinery to carry them out, physically - whether loving one's spouse or deciding what to eat.