IVERMECTIN for dogs:
I remember someone posted awhile back that some dogs can become very ill after taking ivermectin because of some gene mutation. I don’t remember the link that was posted at the time but I am including the info below as a start.
https://www.akc.org/expert-advice/health/heartworm-medication-side-effects/
“Dogs of some herding breeds and some mix-breed dogs can have a genetic mutation that makes them dangerously oversensitive to ivermectin, the active ingredient in some commonly used heartworm prevention medicines for dogs.
Given at the proper doses and under the supervision of a veterinarian, ivermectin is safe for most dogs and is very effective in treating and preventing a number of parasites. However, a dog with the mutation who ingests the drug can have a severe, life-threatening reaction called ivermectin toxicity.
This sensitivity is because of a mutation in what is known as the MDR1 gene. In dogs who have the mutation, the drug crosses the blood-brain barrier and causes neurological damage, which can be lethal.”
There is more info at the link.
Many details here.
It should be noted that my dog was already rx’divm and my current dosage is well within the safe guideline.
Wth that noted...
https://www.veterinarians.org/ivermectin-for-dogs/#ivermectin-dosage-for-dogs
Thank you, Faith.