Posted on 12/08/2022 9:55:38 PM PST by ConservativeMind
A large-scale new study offers a new approach to treating in type 2 diabetes, one that puts patients in charge of their own medication. The Trimaster study is the first to allow people with type 2 diabetes to choose their own medication, after trying three different drugs in succession. It concluded the approach could be a new way of finding the best treatment.
Researchers gave people with type 2 diabetes three commonly-prescribed drugs, each for a 16-week period in turn. Researchers monitored the effect of each drug on the 448 patients' glucose levels, weight and recorded the side effects.
At the end of the study, patients got to choose the drug that worked best for them. Their chosen drug not only lowered glucose most effectively, but also resulted in fewer side effects.
Dr. Beverley Shields said, "Interestingly, we found that the treatment people chose was usually the one which gave them best blood sugar control—even before they knew those results."
Participant Tim Keehner was diagnosed with type 2 diabetes 15 years ago.
"I was given three drugs. The first two didn't work for me at all—in fact, one of them made me feel even worse. Thankfully, from the first moment I took the third drug, I felt different—I had more energy, and I knew it was the right drug for me. I'm still on it today and I'm able to engage in all the sports I love—it's fantastic."
"We've shown that going with the patients' choice results in a better glucose control and fewer side effects than any other approach. When it's not clear which drug is best to use, then patients should try before they choose. Surprisingly, that approach has never been tried before."
The three drugs given to patients in the trial were sitagliptin, canagliflozin, and pioglitazone.
(Excerpt) Read more at medicalxpress.com ...
Optimize everything you can, I say.
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As for me cutting out sugars and carbs is all it took.
Changed carb intake, focusing on macro utrients for my needs. Started 11/7, down 12 lbs, off 2 orals. Using 1/3 of previous mealtime units and half of previous basal. Docs sure won’t tell you that you need far less carbs per meal/snack than “recommended” by the American Diabetes Assoc.
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They need a control group that takes no medication and does one or two 24 hour fasts each week, with no special diet or exercise modifications.
Interesting that they left out Metformin. This sounds like a scam to me. Like “The Pepsi Challenge” but to increase use of expensive drug options, and instead of Coke, they used Mr. Pibb and RC Cola.
I stress diabetics must wear a Libre 2/3, or Dexcom device to constantly monitor their glucose, which helps to pinpoint what your body is doing and when.
The drugs are nice, but it’s important to know which one is going to do the proper thing. And people need to have a bit of tolerance for the side effects, you can’t just feel off for a week and drop the medicine. Diarrhea will go away, other side effects your body may adjust to them with a bit of time.
Actually this is normally done when there is good health care. The physician and patient collaborate on decisions about care.
There is no such thing as an essential carbohydrate.
ZERO is the magic number.
My doctor recommends low carb or keto to all his type two diabetics. I was one of his first patients to introduce him to how effective it is.
BKMRK.
Just don’t make others pay for it if it is controllable by diet, but not being controlled by diet.
Congrats.
Not for everyone, but for most people this is the answer.
I disagree. Vegetables have carbs. I consider those essential given the benefits garnered from the vegetables I consume. But you do you. If zero carbs works for you long term, have at it.
Do you know what you call a doctor who finished in the bottom 5% of his class in Medical school?...
You call him “Doctor”.
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