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To: Steve Van Doorn; nclaurel; Faith65
Having been through the hell of Chronic Fatigue Syndrome myself, I’m not really sure what you are saying about mitochondria not being able to rest. Unless you are referring to the early part of a mitochondrial syndrome where stress has induced thyroid and adrenal dysregulation (because these hormones are trying to fill in the energy space where mitos have become depleted) and you cannot sleep, which in turn puts even more stress on the mitochondria…. either way, when eventually the energy-failure cascade happens (mitos fail + thyroid fails + adrenals fail), you will experience a fatigue that most people cannot even imagine. It goes beyond being “bone tired.” I would describe it as being “soul tired.” There were times when I went to bed hoping to not wake up. In my experience with CFS and mitochondrial syndrome, it’s not that you cannot rest, it’s that you cannot wake up. You cannot stand, you cannot walk… just getting up and taking a shower takes an extraordinary effort, after which you are required to lay down and sleep again. I would fall asleep in meetings and at stop lights.

A mitochondrial failure cascade will eventually lead to major organ failure. Pancreas, liver, heart.. take your pick. These little “battery packs” are VITAL to your health. So vital, in fact, that you could trace just about any disease cascade back to mitochondria. You receive mitos from your birth mother… so if your mother already has problems in the mitochondria, it’s going to transfer to her baby and that child will start life a step behind as far as health and longevity.

I highly recommend researching the work of Dr. Sarah Myhill. She wrote a book that I found online in Wiki version in 2011 and she basically saved my life. Of course, the National Health System in England tried to kick her out of medicine for a while and suspended her medical license, so if you come across that in your research, know that it came directly from the government controllers and Big Pharma. She is now reinstated and her book is available on Amazon. Title: “Diagnosis and Treatment of Chronic Fatigue and Myalgic Encephalitis: It’s Mitochondria, not Hypochondria.” For me, starting on D-Ribose, NAC and Acetyl L-Carnitine provided such relief that I was able to get a start towards healing and begin the rest of her protocol, which is complex and intense, but works.

There is a really great interview with her on YouTube where she covers basically the whole theory and recovery tactics. She is from the Shires and her accent is thick and she speaks really fast, but the info is excellent and she goes deep into the mitochondrial processes. https://youtu.be/efw2zFONk6I Also, many others have joined in on her research, so just searching “Mitochondria and Fatigue” on YouTube will bring up tons of good information.

1,175 posted on 03/22/2022 10:05:44 AM PDT by ponygirl (An Appeal to Heaven )
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To: ponygirl

Having been through the hell of Chronic Fatigue Syndrome myself, I’m not really sure what you are saying about mitochondria not being able to rest. Unless you are referring to the early part of a mitochondrial syndrome where stress has induced thyroid and adrenal dysregulation (because these hormones are trying to fill in the energy space where mitos have become depleted) and you cannot sleep, which in turn puts even more stress on the mitochondria…. either way, when eventually the energy-failure cascade happens (mitos fail + thyroid fails + adrenals fail), you will experience a fatigue that most people cannot even imagine. It goes beyond being “bone tired.” I would describe it as being “soul tired.” There were times when I went to bed hoping to not wake up. In my experience with CFS and mitochondrial syndrome, it’s not that you cannot rest, it’s that you cannot wake up. You cannot stand, you cannot walk… just getting up and taking a shower takes an extraordinary effort, after which you are required to lay down and sleep again. I would fall asleep in meetings and at stop lights.
A mitochondrial failure cascade will eventually lead to major organ failure. Pancreas, liver, heart.. take your pick. These little “battery packs” are VITAL to your health. So vital, in fact, that you could trace just about any disease cascade back to mitochondria. You receive mitos from your birth mother… so if your mother already has problems in the mitochondria, it’s going to transfer to her baby and that child will start life a step behind as far as health and longevity.

I highly recommend researching the work of Dr. Sarah Myhill. She wrote a book that I found online in Wiki version in 2011 and she basically saved my life. Of course, the National Health System in England tried to kick her out of medicine for a while and suspended her medical license, so if you come across that in your research, know that it came directly from the government controllers and Big Pharma. She is now reinstated and her book is available on Amazon. Title: “Diagnosis and Treatment of Chronic Fatigue and Myalgic Encephalitis: It’s Mitochondria, not Hypochondria.” For me, starting on D-Ribose, NAC and Acetyl L-Carnitine provided such relief that I was able to get a start towards healing and begin the rest of her protocol, which is complex and intense, but works.

There is a really great interview with her on YouTube where she covers basically the whole theory and recovery tactics. She is from the Shires and her accent is thick and she speaks really fast, but the info is excellent and she goes deep into the mitochondrial processes. https://youtu.be/efw2zFONk6I Also, many others have joined in on her research, so just searching “Mitochondria and Fatigue” on YouTube will bring up tons of good information.


Thanks very much, ponygirl.
Bkmk for more research.


1,181 posted on 03/22/2022 10:42:15 AM PDT by Faith65 (Isaiah 40:31 )
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To: ponygirl

Would you like to post that comment about CFS on the Natural Health thread? If you do, let me know and I will ping the list.

https://freerepublic.com/focus/bloggers/3735908/posts?page=1213#1213


1,191 posted on 03/22/2022 11:15:14 AM PDT by little jeremiah (Don't worry about anything. Worry has never solved any problem or moved any stone. )
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To: ponygirl

Thank you, Bkmk 4 later.


1,193 posted on 03/22/2022 11:17:48 AM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change with out notice.)
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To: ponygirl
I've listened to Dr. Sarah Myhill a long time ago she is really good on what mitochondria needs to be healthy. Such as the development of the membrane or coenzyme Q. She is clearly on the right track. This report explains the process how the body creates coenzyme Q.
Myhill and Reiter differ is on levels of Melatonin Myhill believes you can over dose. I'm with Reiter on this. I don't know what else the differ on.

Chronic Fatigue Syndrome and Fibromyalgia are very broad terms. Doctors love to use broad terms as they want to treat the symptoms.

Here is the bases on how Melatonin works
Melatonin - sleep cycles Russel J. Reiter
https://www.youtube.com/watch?v=I7YIRqTNmuY&t=1s
This is more details from Loh and Reiter (heavy reading)
mitochondria health Melatonin: Regulation of Biomolecular Condensates in Neurodegenerative Disorders
https://www.mdpi.com/2076-3921/10/9/1483/htm
1,264 posted on 03/22/2022 3:18:43 PM PDT by Steve Van Doorn (*in my best Eric Cartman voice* 'I love you, guys')
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