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Vitamin B12 deficiency increases risk of depression
Medical Xpress / Trinity College Dublin / British Journal of Nutrition ^ | Dec. 14, 2021 | Eamon Laird et al

Posted on 12/14/2021 2:22:38 PM PST by ConservativeMind

Scientists have published new research which examines the relationship between folate and vitamin B12 status and its associations with greater prevalence of depressive symptoms in a group of community-dwelling older adults. The study shows that low vitamin B12 status is linked to depressive symptoms, but shows that folate is not associated with depression.

Vitamin B status in Ireland

Deficiency and low status of the B-vitamins such as folate and vitamin B12 are highly present in older people. In Ireland, one in eight older adults are reported to have low B12 status, while low dietary intake and low blood status have been reported throughout all age groups in the Irish population. Some of the negative consequences of low B12 status can include megaloblastic anemia, impaired cognitive function, or damage to the protective covering (myelin sheath) that surrounds the nerve fibers of the brain. Understanding the link between folate or low B12 status and depression in later life is important as depression is a risk factor for functional decline, admission to residential care and early death.

The study uses data from TILDA, and examines participants aged 50 years and over who were assessed at Wave 1 of the study and who provided measurement of plasma folate and plasma B12 and screening for depression. Researchers observed that those with deficient-low B12 status had a 51% increased likelihood of developing depressive symptoms over 4 years.

The study finds that low B12 status is associated with a significantly greater risk of depressive symptoms over four-year period, but no such associations were observed for folate.

Other factors that influence micronutrient status in older adults included obesity, medication use, smoking, wealth, gender and geographic location.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: b12; depression; vitb12
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If in doubt, consider getting tested.
1 posted on 12/14/2021 2:22:38 PM PST by ConservativeMind
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To: Pete from Shawnee Mission; Mazey; ckilmer; goodnesswins; Jacquerie; Jane Long; BusterDog; jy8z; ...

The “Take Charge Of Your Health” Ping List

This potentially high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to implement for your benefit.

Please email or private message me if you want on or off of this list.

2 posted on 12/14/2021 2:22:58 PM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

B-complex pills are good to ingest regularly.


3 posted on 12/14/2021 2:28:09 PM PST by entropy12 (President Trump was the best president in my life time of 81 years and counting..)
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To: ConservativeMind

Just eat plenty of beef, tuna, salmon, eggs, etc.


4 posted on 12/14/2021 2:28:12 PM PST by Repeal The 17th (Get out of the matrix and get a real life.)
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To: entropy12

Good energy booster.


5 posted on 12/14/2021 2:29:33 PM PST by RushIsMyTeddyBear (I'm in the control group. I identify as "vaccinated".🤡)
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To: ConservativeMind

This might explain why I’ve never met a happy vegan...


6 posted on 12/14/2021 2:29:42 PM PST by mewzilla (Those aren't masks. They're muzzles. )
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To: mewzilla

I was thinking the same thing.


7 posted on 12/14/2021 2:32:57 PM PST by Republican Wildcat
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To: ConservativeMind

They’ve known this for decades. That’s why many people get the shots.

If the parietal cells don’t produce intrinsic factor the stomach acid destroys all the B12 causing a deficiency.


8 posted on 12/14/2021 2:33:47 PM PST by tired&retired (Blessings )
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To: ConservativeMind

“Other factors that influence micronutrient status in older adults included obesity, medication use, smoking, wealth, gender and geographic location.”

Well, if you’re a poor, fat, smoker who lives in a place with little sunshine, you’re probably going to be depressed no matter how high your B12 levels are.


9 posted on 12/14/2021 2:37:53 PM PST by Boogieman
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To: mewzilla

Or maybe its because most of them are liberals.


10 posted on 12/14/2021 2:38:35 PM PST by Starboard
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To: Starboard

IT’S IN PORK.-the other white meat.


11 posted on 12/14/2021 2:39:58 PM PST by DIRTYSECRET
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To: ConservativeMind

I get some 12mcg 500% in my ‘B Complex’. Wonder what is enough also if that’s included in a regular yearly lab test and what it would be listed as. Guess I need to ask my doctor. Thanks for info.


12 posted on 12/14/2021 2:49:28 PM PST by TribalPrincess2U
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To: ConservativeMind

Good article. I take a B12 gummy each morning. I take enough supplements in pill form, have never liked swallowing them and I always have to have some food in my tummy. The B12 gummy first thing is perfect for me.


13 posted on 12/14/2021 2:50:30 PM PST by MomwithHope (Forever grateful to all our patriots, past, present and future.)
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To: ConservativeMind

Vitamin D supplements or sunshine is highly effective on clinical depression. Most Americans over 45 need B12 supplements.


14 posted on 12/14/2021 3:11:52 PM PST by arthurus (covfefe uou)
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To: tired&retired

They’ve known this for decades. That’s why many people get the shots. If the parietal cells don’t produce intrinsic factor the stomach acid destroys all the B12 causing a deficiency.”

indeed ... and in the case of pernicious anemia, which is an autoimmune disorder in which the body develops auto-antibodies against the gastric parietal cells and/or intrinsic factor itself, the body cannot absorb dietary B12 and those affected must take injections of B12 to prevent death ... i know because i’m one of those persons ... i always joke that if you HAVE to have a fatal illness, pernicious anemia is the best one to have ...


15 posted on 12/14/2021 3:27:30 PM PST by catnipman (Cat Nipman: Vote Republican in 2012 and only be called racist one more time!)
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To: catnipman

I read a journal article earlier today that said that many people getting shots could take tablets instead.

Not sure I agree..


16 posted on 12/14/2021 3:46:19 PM PST by tired&retired (Blessings )
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To: mewzilla
This might explain why I’ve never met a happy vegan...

Why did the vegan cross the road?

To get to the other side to tell you "I am a vegan."

17 posted on 12/14/2021 4:01:36 PM PST by frank ballenger (You have summoned up a thundercloud. You're gonna hear from me. Anthem by Leonard Cohen)
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To: tired&retired

“I read a journal article earlier today that said that many people getting shots could take tablets instead. Not sure I agree..”

indeed ... lots of claims that sublingual B12 is good enough, but my internist, who’s actually a specialist in pernicious anemia, says not using injectable B12 for those who have actual pernicious is complete BS ... both he and my regular doc are big believers in frequent, large doses of injectable B12 for pernicious anemia ...

i inject 20,000 units once a week, AND i inject compounded methylcobalamin, one of the two active forms, rather than the “officially” recommended 1,000 units once a month of cyanocobalamin, which is the shelf-stable form that regular pharmacies like to stock, but has to be converted by the body to methylcobalamin ...


18 posted on 12/14/2021 5:13:45 PM PST by catnipman (Cat Nipman: Vote Republican in 2012 and only be called racist one more time!)
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To: catnipman

I would go a step further and investigate why the parietal cells are not working properly.

I’ve had patients where the cause was cancer in the fundus where they are located that went undetected for years.


19 posted on 12/14/2021 5:19:24 PM PST by tired&retired (Blessings )
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To: tired&retired

“I would go a step further and investigate why the parietal cells are not working properly.”

no big mystery for me: MASSIVE antibodies to both the gastric parietal cells and intrinsic factor, PLUS i’ve got hashimoto’s thyroiditis, sjogren’s syndrome, atopic dermatitis, gluten allergy, i.e., multiple autoimmune syndrome ...


20 posted on 12/14/2021 7:28:10 PM PST by catnipman (Cat Nipman: Vote Republican in 2012 and only be called racist one more time!)
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