Posted on 10/18/2021 5:27:19 PM PDT by ransomnote
You can keep making that false claim - you’ll keep getting called on it.
Sorry, Furry. You 'calling on it' doesn't make a fact a not fact.
But thank you for playing.
#AFactsAFact
Please reply with a link to the coronavirus Sars-cov-2 genetic sequence and the delta variant sequence. I hear that is different by 16 nucleosides, would be to see it.
Thanks in advance,
3
“Please reply with a link to the coronavirus Sars-cov-2 genetic sequence and the delta variant sequence. I hear that is different by 16 nucleosides, would be to see it.”
Hope you can find what you’re looking for in the links below.
https://www.biorxiv.org/content/10.1101/2020.04.26.063024v1.full
https://www.biorxiv.org/content/10.1101/2021.09.11.459844v3.full
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00170-5/fulltext
https://www.publichealthontario.ca/-/media/documents/ncov/epi/covid-19-sars-cov2-whole-genome-sequencing-epi-summary.pdf?la=en
https://www.ncbi.nlm.nih.gov/sars-cov-2/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483667/
https://www.nature.com/articles/s41467-021-22905-7
I came across an interesting article in Science earlier today. It’s about a cancer survivor that took a year to clear the virus and as it circulated in her system it mutated by almost 500 nucleotides. Lord knows if we’ll ever be rid of this Chicom bioweapon.
https://www.science.org/content/article/cancer-survivor-had-longest-documented-covid-19-infection-here-s-what-scientists-learned
Oops. Forgot one other I had.
https://nextstrain.org/ncov/gisaid/global?c=gt-ORF1a_1640,2287,2930&label=clade:21A%20%28Delta%29
Bear with me now, I’m still learning math
2019 is 15% less than 3,358,814 or 2019 was 2,824,763 total
15.9% increase equals 3,358,814 minus 2,824,763 or 534,051.
therefore, 15.9% or 534,051 = 100% of the increase
and 11.3% = 2/3’rds to 3/4’ths of the increase
common denominator 3 chosen: 11.3% / 15.9% = 2/3
2/3 x 534,051 = 356,312
common denominator 4 chosen: 11.3 / 15.9% = 3/4
3/4 x 534,051 = 400,528
which gives us a ballpark range that puts the CDC figure of 377K right in the middle and so makes sense
going further, 22% under age 64 x 377K = 82K or over 370/day
I understand your thousands thousands number, and I get how you got to 397,250
But I think where you tripped up is on not translating the percentages
so using your number of 397K x 3/4 = 298K and x 2/3 = 265K
then going with ballpark under 65 at 22% that would be 65K and 58.3K respectively, versus ‘my’ number of 82K. which is 10x your number.
yes?
As you know, I live in the land of groundhog day where every day is a lockdown of some sort for the last 18 months. As such, I am adamently adverse to locking down areas that have little spread.
However, I think a lot of apathy is expressed towards ‘the elderly’ deaths. Yes, they were the highest casualties last year, no doubt. (maybe not so true this year?) But does that make their deaths less significant? Do people lose their value when they hit 65 even while they still remain the main captains of industry and babysitters (and wallets) for their working (or not) sons and daughters? We ran into nursing homes to give them shots, wanted or not, conscious or not, because the HCW/first responders were terrified a patient would get them sick, but when it’s time for HCW/FRs to do the same, they balk at protecting the elderly that protected them, even throwing a fit over the ‘testing biweekly’ option while insisting kids get take on the burden that should be squarely on the shoulders of adults in a moral society. Whether those adults choose vaccination, monoclonals or staying away from crowds. I think we should value elderly deaths more and not excuse them with a wave of the hand as if we’re ‘normalizing’ death. jmo
Thx - helpful
NIH has tracked mutations in many (all?) genes in sars cov-2.
I looked at the spike protein mutations they have found, and there are thousands. it is a much smaller number of these mutations that are commonly recurring. (40ish)
The spike protein was a bad choice for a vaccine, because mutations there are less deleterious. IMO
It seems there are many sequencing exercises happening, and they are being tracked/cataloged.
Is the nucleoside sequence used in the vaccine being adjusted to the prevailing mutations, or are they still the original type from the wuhan lab?
It seems the vaccine would predictably lose efficacy if it stayed with a static nucleoside sequence. would it also be a new drug with every update, needing new approval?
Maybe that is why the sequences used in each vaccine is kept secret from the public.
—- complicated stuff—-
However, I think a lot of apathy is expressed towards ‘the elderly’ deaths. Yes, they were the highest casualties last year, no doubt. (maybe not so true this year?) But does that make their deaths less significant?
It means that you shouldn't force tens or hundreds of millions of people at very little risk, to get experimental gene therapy, or lose their jobs -- while winking at their employers that you won't require them to record adverse events...
When almost everybody in the workplace, who is being forced to get the jabs, is under 65, and at MUCH lower risk than the old.
I looked at the spike protein mutations they have found, and there are thousands. it is a much smaller number of these mutations that are commonly recurring. (40ish)
Interesting. I had no idea there were that many. For the time being, delta has crowded out all others with some 95%+ of infections. Hopefully, between vaccination and natural immunity, this disease becomes endemic and eventually fades away. Hopefully.
The spike protein was a bad choice for a vaccine, because mutations there are less deleterious. IMO
From an older article I've read, the researchers chose the spike protein to guard against ADE. And so far both the adenovirus DNA and mRNA vaccines have proven more efficacious than the Sinovac whole virus approach.
"From the early stages of COVID-19 vaccine development, scientists sought to target a SARS-CoV-2 protein that was least likely to cause ADE. For example, when they found out that targeting the nucleoprotein of SARS-CoV-2 might cause ADE, they quickly abandoned that approach. The safest route seemed to be targeting the S2 subunit of the spike protein, and they ran with that, wrote Derek Lowe, PhD, in his Science Translational Medicine blog "In the Pipeline." Scientists designed animal studies to look for ADE. They looked for it in human trials, and they've been looking for it in the real-world data for COVID-19 vaccines with emergency use authorization."
It seems there are many sequencing exercises happening, and they are being tracked/cataloged.
As I had speculated earlier in this thread, COVID is probably the most genetically studied pathogen in history. With the possible exception of AIDS I suppose.
Is the nucleoside sequence used in the vaccine being adjusted to the prevailing mutations, or are they still the original type from the wuhan lab?
The current vaccines haven't yet been tweaked from the original version. I know both Moderna and Pfizer have trials in progress tailored to the current variants of concern. I suspect those will not be needed and could be reformulated once again should one of the delta sub-variants or other variant of concern arise. IMO.
It seems the vaccine would predictably lose efficacy if it stayed with a static nucleoside sequence. would it also be a new drug with every update, needing new approval?
The approval process for a "tweeked" formulation would be handled as the annual Flu vaccines are. Efficacy and safety are again confirmed, but the process is expedited. That's my understanding at least.
—- complicated stuff—-
LOL. Yes, it is. Especially for this old tip & ring man. I'm just glad much smarter people than I are working to defeat this Chicom bug.
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