Posted on 04/06/2021 12:21:27 PM PDT by Red Badger
A revolutionary technology developed within the Trabolsi Research Group at NYU Abu Dhabi (NYUAD) could dramatically improve the wellbeing of diabetic patients: an insulin oral delivery system that could replace traditional subcutaneous injections without the side effects caused by frequent injections.
Using prepared layers of nanosheets with insulin loaded in between layers to protect it, the researchers developed gastro-resistant imine-linked-covalent organic framework nanoparticles (nCOFs) that exhibited insulin protection in the stomach as well in diabetic test subjects whose sugar levels completely returned to normal within two hours after swallowing the nanoparticles. Led by NYUAD's Research Scientist Farah Benyettou and Program Head of Chemistry Ali Trabolsi, the findings were published today in Chemical Science.
Compared to the two FDA-approved technologies for the oral delivery of insulin, the system developed at NYUAD is biocompatible, highly stable in the stomach, specific, and able to deliver the right amount of insulin based on the diabetic subject's blood sugar levels. This treatment represents a step forward in treating this disease, which is the seventh leading cause of death worldwide.
"Our work overcomes insulin oral delivery barriers by using insulin-loaded nCOF nanoparticles which exhibit insulin protection in the stomach as well as a glucose-responsive release," said Benyettou. "This technology responds quickly to an elevation in blood sugar, but would promptly shut off to prevent insulin overdose and will dramatically improve the well-being of diabetic patients across the UAE and worldwide," she added.
More information: Farah Benyettou et al. In vivo oral insulin delivery via covalent organic frameworks, Chemical Science (2021). DOI: 10.1039/D0SC05328G Journal information: Chemical Science
How to Reverse Type 2 Diabetes Naturally | Jason Fung
5,189,207 views•Dec 10, 2013
Reverse Type 2 Diabetes naturally, without medications. It is a curable disease, but as a dietary disease, it demands a dietary treatment. The principles including fasting and weight loss are outlined. Dietary modification is the cornerstone of reversing type 2 diabetes. For more, see https://thefastingmethod.com
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It will be interesting to compare the cost of this per pill vs the insulin jab. I suspect the jab will win with ease.
What about Type 1? It’s like a whole different disease.
In people with type 1 diabetes, the immune system mistakes the body’s own healthy cells for foreign invaders. The immune system attacks and destroys the insulin-producing beta cells in the pancreas. After these beta cells are destroyed, the body is unable to produce insulin.
So you have to add immune system support and healing protocols to the dietary modification to reduce blood sugar. One only needs insulin when one has excess blood sugar. Dr. Jason Fung’s approach reduces that.
Yup it’s probably going to be expensive as all get out.
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