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HERE's A BRIEF EXPLANATION OF HOW HYDROXYCHLOROQUINE AND THE OTHER PARTS OF THE COCKTAIL WORK:

Let’s start with a few basic things we know about COVID-19.

1. The disease has three phases. The first is an upper respiratory infection that many people recover from without medical support. The second is respiratory inflammation which may cause clots. The more severe form is caused by an abnormal immune system response that can lead to sepsis, organ damage, and death.
2. COVID-19 binds to the cell receptor ACE-2. So did the viruses first cousin, SARS. This is how it enters a cell.
3. Coronaviruses are RNA viruses that need to hijack the body cell’s function to replicate or make new viruses

America’s Frontline Doctors are advocating for the use of hydroxychloroquine, zinc, and azithromycin early in the illness and prophylactically. The most emphatic physician did overstate her case calling the drug combination a “cure.” However, if it can be verified that all of her 350 patients are still alive, then her patients have been cured.

Chloroquine and hydroxychloroquine have the same pharmacological action in the body. The latter is considered to be safer, which is why it is being used. Both drugs are also zinc ionophores. This means if the virus successfully enters the cells, they hold open the passage and pull more zinc in. Zinc interferes with the virus’s ability to replicate or photocopy its RNA. The NIH knows that too. Archived for posterity here.

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Azithromycin or doxycycline both have an anti-inflammatory effect. Since the outpatient disease can include inflammation in the lungs, these are added to the treatment. Some doctors are now using inhaled steroids, also an anti-inflammatory, such as budesonide, to treat this symptom.

All of these drugs have excellent safety profiles, a long history of use, and are generic. This means they are inexpensive and could easily be made widely available. This was summarized by Dr. James Todero who also spoke at the press conference. I am including his entire commentary here because I think it is important.

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