Posted on 05/07/2020 6:32:35 PM PDT by RaceBannon
Corona Virus Daily Thread #51 COVID-19 5/07/2020
Saw Interesting theory..mt everest climbers use viagra to save their life. Could it do the same with covid 19
Researchers testing inhaling nitrous oxide for covid ...and sure enough..in the story was a mention of viagra in 90s development
Should the New Case drop way lower before the Death Rate drops to the low of 1008?
Wonder if the new cases is the less dangerous strains. Looks like Ca is still climbing with new cases.
Max performer an otc ED pill has some of the same ingredients we have been talking about including korean red ginsing.
Not saying take it. Just think it is interesting
It would still be a nice way of avoiding the Dem and RINO hesitancy to re-open at something resembling a good pace to get our economy back up. Each state’s idiot governor can see how the 51%-or-more interstate commerce businesses affect things. If the state properly prepared to handle any resulting spikes, and the open businesses act prudently to mitigate spread, then there would be no more excuse to eventually re-open the entire state by sometime this summer.
No excuse NOT to eventually reopen the entire state by sometime this summer . . .
If it saves your life for more than 4 hours, consult another physician.
Wuhan will test the entire population after new cases are detected
The 13 districts of Wuhan have ten days to start testing their inhabitants. At stake are the new cases that emerged over the weekend and raised fears of a second wave.
The hearing. Since I can’t seem to find a thread on this, here goes.
Lamar is a life time career politician. He’s more worried about getting UT open so he can have football.
Whew, Sen. Murray was a real witch who wants this COVID-19 hearing to focus on the big bad orange guy who has failed at every step. Someone should ask her how many ventilators and PPEs she bought during her time.
Fauxi is up. He’s still on vaccines but now has modified that to “if” we can make a vaccine. Guess he heard from Boris Johnson we may not be able to create a vaccine. Says some vaccines may enhance virus (uh huh, those who has SARS vaccine in China were hit worse).
CDC up. Yada, yada. Waste of air. “We need to rebuild our health system.” Uh, yeah, sort of falls into the CDC jurisdiction who wasn’t prepared for an ingrown toe nail much less this monster.
Who’s that wearing Birx’s scarf as a mask?
Hearing
Adm. Giroir - shipping swabs, etc. to states.
Dr. Hahn, FDA - Has bad throat clearing. Monitoring market place of fraudulent tests. Hmm, maybe he should have been on 3M shipping PPEs to China and stopping potentially infected masks being shipped to our healthcare workers. He’s a Fauxi fan.
Hearing Questions
How to persuade students back to colleges? Fauxi - vaccine won’t be available by Aug. so going with passive transfer this coming term. He didn’t want the question so asked the baton to be passed to the Adm. and Adm. wants to pass it to the Dr. Adm. says pooling samples would work, waste water testing of dorms. Dr. Redfield - wellness education.
Bottom line, we’re on our own with this.
Ugh, Trump hating Sen. Murray - Fauxi “gateway and dynamics” to prematurely reopen states and will have little spikes. No doubt when mediation is dropped that cases will reappear. Need capabilities to respond to the inevitable. She turns to Adm. while badmouthing this administration. Adm. says they’ll get 12 million tests out to states as they’re opening. She keeps interrupting and is over time.
Ok, a thread is up so going there.
Dr Louis P Coates
10 hrs ·
Coronavirus Update 5/12/2020 - BTHO COVID-19
So today at the time of this writing there are 18.196 new cases today with 1008 deaths. Cases and deaths still are significantly down to lowest levels in a long time. Today the mortality rate is at 5.54%. We also have 16,514 in critical condition still high so the fatality numbers will likely stay high a while longer. So the overall mortality rate dropped a little to 5.90%.
We also have now had 262,225 people recovered from this virus and should now have some degree of immunity from this horrific disease.
Locally, in Texas we are still plateaued and we are waiting for the downside of the curve. We had 1155 new cases and 26 new deaths with a slightly decreasing mortality rate of 2.7%.
Because antibody testing is being added to the numbers we are monitoring active cases. So we have 17,624, barely up from 17,142 active cases in Texas. The number of active cases has leveled off around 17k over the past 3 days. In addition we have 21,814 recovered now. So active cases are very stable. We are still many times under both the number of hospital beds and ICU beds needed.
Today in Dallas county 253 new cases and 2 new deaths. Harris county with 298 new cases and 7 new deaths. Collin county with 31 new cases and 1 new death. Denton county with 8 new cases and no new deaths. Tarrant county with 485 new cases and 2 new deaths. Brazos county with 9 new cases and no new deaths. Travis county with 44 new cases and 5 new deaths. Fort Bend county with 15 new cases and 2 new deaths. Also Bexar county with 66 new cases and 0 new deaths.
For the newbies we are predicting an overall fatality rate somewhere in the 0.3 to 0.7 range when we finally correct the denominator. The real question is just how much of the population is already infected 2%, 5%, 10% etc.
We have discussed it before but frequently asked, can people who had COVID-19 get re-infected?
In order to determine this we infected 4 rhesus monkeys with the SARS-COV2 virus and measured viral loads of SARS-COV2 with nasal and anal swabs which peaked around 3 days after initial infection. Then 1 monkey was destroyed to see what all parts of the body contained the virus Then after recovery they measured viral loads, when negative at 28 days they reinfected the 3 monkeys and found they showed no physical or radiological signs of infection. In addition they are tested again with nasal and anal swabs and they all had negative viral loads. So this is extremely promising showing that we will very likely develop immunity to the virus. So this states that those that have had symptomatic infections of Covid-19 will likely have some form of immunity from reinfection of the SARS-COV2 virus. This is the basis for developing a vaccine! No immunity, essentially means no vaccine. For those of you who are wanting human testing on immunity they are not going to purposely try to reinfect humans simply to test immunity. But people with symptomatic Covid-19 infections that tested positive and get reinfected will be the only way we can assess in humans.
https://www.biorxiv.org/content/10.1101/2020.03.13.990226v1
The real questions now are how long will the immunity last?
A month, a few months, a year, 2 years, 5 years, or even lifelong we simply don’t know. Also if you test positive for the SARS-COV\2 IgG do you have immunity while we think so, this we don’t know. What if the IgG is positive from a cross reaction to other coronavirus? What if it is a false positive from the test itself? Also what if you were asymptomatic will you mount a strong enough immune response to have any immunity from reinfection while we believe so we simply don’t know at this time. So we need further testing which is currently underway before any long term statements on immunity can be made.
Researchers at Mount Sinai who are currently enrolling 15,000 patients for plasma donation, so far they have tested 624 people so far and only 511 had high levels of antibodies, 42 had low levels and 71 had none initially but 64 were found to have weak antibodies a week later. So this brings into question if people who were asymptomatic initially will mount a strong enough response to have any immunity to a recurrent infection.
https://gabio.org/after-recovery-from-the-coronavirus-most…/
Also what if the virus mutates?
Well luckily historically the coronavirus is a slow mutating virus. With only minor mutations that usually do not affect our antibodies ability to bind the M or S (spike) proteins which are the antigens on the virus. If you remember from our immunology blog a month or so ago we those are where the antibodies bind to the virus to either inactivate or destroy the virus. These are also how the virus binds to and gets into our cells. So a mutation here could be very dangerous. FIrst it could make our antibodies unable to attach to the virus. Secondly, it could enhance the virus’s ability to infect our cells. Lastly, and hopefully, it could disable the viruses ability to infect our cells.
Unfortunately we actually did recently see a small mutation in the S (spike) protein so this is definitely not good news. The implication of this mutation is currently being studied. I am not a biochemist or virologist but if these types of mutations continue this could provide difficulty in developing a reliable vaccine and make people susceptible to a second infection if their antibodies do not recognize the S (spike) protein. So let’s hope we don’t see anymore of these types of mutations.
https://www.biorxiv.org/…/10.1…/2020.04.29.069054v1.full.pdf
N-acetylcysteine potentiates the antihypertensive effect of ACE inhibitors in hypertensive patients.
https://www.ncbi.nlm.nih.gov/pubmed/12361192
k2aggie07In reply to JimbosHatBarelyFits • 12:09a, 5/12/20AG
My wife is an optometrist. She says viruses can cause inflammation which can lead to a cascade effect which can cause a retinal detachment in an extreme case. This is not common.
CDC keeps cutting out in his testimony. Cant believe there isnt better technology
rand paul question cant even be understood because of echoing
what a messed up show here.
rand paul gently ripping Fauci
facui gently ripping rand paul back...and brings up children and kawaski disease
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