Posted on 03/25/2020 9:23:43 AM PDT by kiryandil
In vitro is not in vivo. I still want to know about the patients we have had right now. The data is there. Where is the paper?
Thank you for calling me names. You have certainly convinced me!
What is that - about a half hour from now?
Where are the CNN bananas?
Take a nap, dad.
Or go read the fake Chinese propaganda article by Rosie McCall, NeverTrumper and Resistance warrior.
Maybe we could axe the old Oranges coot to bend over and let us check...
Maybe we could axe the old Oranges coot to bend over and let us check...
Thalidomide was discovered by professionals at the German pharmaceutical company Chemie Grünenthal (now Grünenthal GmbH) circa 1953. The company had been established as a soap maker after World War II ended, to address the urgent market need for antibiotics. Heinrich Mueckter, who was a known Nazi war criminal,[29] was appointed to head the discovery program based on his experience working with the German army's antiviral research. While preparing reagents for the work, Mueckter's assistant Wilhelm Kunz isolated a by-product that was recognized by pharmacologist Herbert Keller as an analog of glutethimide, a sedative. The medicinal chemistry work turned to improving the lead compound into a suitable drug: the result was thalidomide. The toxicity was examined in several animals, and the drug was introduced in 1956 as a sedative; it was never tested on pregnant women.[30]As that weird angry girl said, "how dare you."
No you do not know what science is. That is clear. What you mean by science is that things comply with the parameters you are most comfortable and give you the illusion of control. That is much too narrow a view of science.
Science refers to a system of acquiring knowledge. This system uses observation and experimentation to describe and explain natural phenomena.
In medicine there are many forms of inquiry not just the one path you are comfortable. When we think about how many studies of the type you insist are found to be falsified we see the illusion of precision & infallibility exposed.
Snicker...if I have stopped contributing to knowledge my job here is done : )
Lol
Again, you have a right to ask whatever academic questions you feel like asking, and doing as much investigating as you possibly can in your own time.
But it won’t slow the good judgment or decisive actions of great leaders like President Trump, or anyone else with solid intuition about treating COVID-19 with hydroxychloroquine/azithromycin.
French study
https://www.freerepublic.com/focus/f-chat/3825971/posts?page=1#1
Drs in New York hospitals
https://www.freerepublic.com/focus/f-news/3826642/posts?page=1#1
Science is hard.
Let's start by defining the problem. The problem is that the increasing rate of infection coupled with the necessity of putting a considerable percentage on ventilators ( a percentage that may be 2%) will result in running out of ventilators and will double the death rate.
If the nation has 100,000 ventilators, then at most we can tolerate 5 million infected patients before running out of ventilators. If 10 million are infected, then we will have a need for 200,000 ventilators and we will have probably 150,000 deaths; one-third solely due to the lack of ventilators.
If 50 million are infected at one time, then nearly one million will die due to lack of ventilators. That is the problem that must be solved.
The French study claimed that 6 out of 6 patients receiving the Trump pills were cured. It also said that another six patients were dropped from the treatment group. I think it also said three of them were critical.
If those three had been kept in the study and died, then the death rate of the treated patients would have been 3 out of 30, or 10%. The French study is not only "anecdotal" it could very well be what we in the science biz call "wrong".
As for the guy who successfully treated 350 patients, there is no control group. Where is the population equivalent to his treatment group to show that his results are superior. Did I read that his patients were all treated outside a hospital? Doesn't that strike anybody as an important detail? Would that not be a way to get a wrong answer to the problem?
The assumption that those eager to pursue this "cure" are making is that there is no cost to being wrong. I would submit that the resources put on a wrong solution are potentially very costly.
In my life, when faced with a problem that must be solved, I would very often try to do EVERYTHING that might contribute to the solution. Rarely would I have the resources of time or money to do that. Choices have to be made.
It may well be that Trump's pills are the best choice right now. But the damage that I described above will not be mitigated if that choice is wrong. The intuition is strong on this one. The science is not yet as strong.
That’s pretty much it in a nutshell.
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