Several solutions if you've just got to use them are: (1) Lower the dose to where you don't get the pain, (2) Check into the enzymes that will help you metabolize them, (3) Give up grapefruit or any other food or food byproduct that creates an overdose situation.
We did try dosing adjustments, and even different brands. I was aware of the grapefruit issue before I started taking them, so that wasn’t an issue. BUT...# 2 is something new to me, I’ll look into it. Thanks.