Intestine crucial to function of immune cells, research shows (MS? RA?)

University of Toronto ^ | December 12, 2011

[decimon]

TORONTO, Canada—Researchers at the University of Toronto have found an explanation for how the intestinal tract influences a key component of the immune system to prevent infection, offering a potential clue to the cause of autoimmune disorders like rheumatoid arthritis and multiple sclerosis.

"The findings shed light on the complex balance between beneficial and harmful bacteria in the gut," said Prof. Jennifer Gommerman, an Associate Professor in the Department of Immunology at U of T, whose findings were published online by the scientific journal, Nature. "There has been a long-standing mystery of how certain cells can differentiate between and attack harmful bacteria in the intestine without damaging beneficial bacteria and other necessary cells. Our research is working to solve it."

The researchers found that some B cells—a type of white blood cell that produces antibodies—acquire functions that allow them to neutralize pathogens only while spending time in the gut. Moreover, this subset of B cells is critical to health.

"When we got rid of that B-cell function, the host was unable to clear a gut pathogen and there were other negative outcomes, so it appears to be very important for the cells to adopt this function in the gut," said Prof. Gommerman, whose lab conducted the research in mice.

Textbook immunology—based mostly on research done in the spleen, lymph nodes or other sterile sites distant from gut microbes—has suggested that B cells develop a specific immune function and rigidly maintain that identity. Over the last few years, however, some labs have shown the microbe-rich environment of the gut can induce flexibility in immune cell identity.

[gaijin]

whoops! I didn’t finish;

Leave the jar in the dark cupboard for 3 weeks, maybe agitate it every 5 days or so, and check the progress.

After 3 (or 10, or more) weeks, strain off the tincture from all the bits, and that’s your medicine.

Put into eye-dropper bottles, label, and use.

Don’t drink it like a beverage —especially in the beginning when people are normally loaded up with yeast and fungi, the BW tincture will be killing lots of bad stuff in ya, and those dead guys release endotoxins.

So go slow in the beginning —you might get a rash, and a headache. Ironically you’re getting better, but if it gets unbearable, slow down a bit, or even stop for a time.

Yeast and fungi contain endotoxins —go at the speed that suits you, and monitor how you feel and look.

The most common reaction is a skin rash or flaking on the arms and chest —this is the yeast/fungi die-off.