Posted on 07/24/2010 8:11:21 PM PDT by nickcarraway
A new study has shed light on the interaction between broccoli consumption and reduced prostate cancer risk.
Researchers have found that sulforaphane, a chemical found in broccoli, interacts with cells lacking a gene called PTEN to reduce the chances of prostate cancer developing.
Richard Mithen, from the Institute of Food Research, an institute of BBSRC, worked with a team of researchers on Norwich Research Park, UK, to carry out a series of experiments in human prostate tissue and mouse models of prostate cancer to investigate the interactions between expression of the PTEN gene and the anti-cancer activity of sulforaphane.
"PTEN is a tumour suppressor gene, the deletion or inactivation of which can initiate prostate carcinogenesis, and enhance the probability of cancer progression. We’ve shown here that sulforaphane has different effects depending on whether the PTEN gene is present,” he said.
The research team found that in cells, which express PTEN, dietary intervention with SF has no effect on the development of cancer.
In cells that don’t express the gene, however, sulforaphane causes them to become less competitive, providing an explanation of how consuming broccoli can reduce the risk of prostate cancer incidence and progression.
"This also suggests potential therapeutic applications of sulforaphane and related compounds,” Mithen added.
The study appears in BioMed Central’s open access journal Molecular Cancer.
hmmmmmm
THX THX.
Well, guess that explains my recent clear colonoscopy (when my aunt died of colon cancer)...I eat broccoli or broccoli slaw at least once a week.
So thankful that I LOVE it!!
Bump
Bump
PS... not that I would have a prostate! :)
Lamh Foistenach Abu!
Well, hopefully it inhibited it’s growth. Hope you are doing well with that.
Stir-fried chicken, broccoli and onions with stirfry sauce over brown rice is great.
Lamh Foistenach Abu!
I like broccoli. It's....good...for...you.....
I love plain ol’ slaw ( cabbage )....
Never had broccoli slaw...
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