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The Inner Life of a Cell Video - FR Folding@Home Project Update
Harvard University Multimedia Production Site ^ | 04/10/2007 | Alain Viel and Robert A. Lue

Posted on 04/15/2007 7:39:44 PM PDT by texas booster

Inner Life of a Cell

Inner Life of the Cell: Animation conception and scientific content by Alain Viel and Robert A. Lue.

Animation by John Liebler/XVIVO.

SIGGRAPH Award Winning Video


TOPICS:
KEYWORDS: alzheimers; cell; fh; foldinghome; innerlifeofacell
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Great video depicting interactions inside a cell, especially the cellular reaction to swelling.

It is geared toward training doctors and researchers, and gets pretty heavy into the organized structure of cells.

In Folding@home the goal is to simulate the actual atoms and molecular forces that force a protein to fold in a particular manner. When the molecules of a protein unzip to replicate or to contact another protein is the focus of our research. F@H looks at the folds a protein makes and the forces that allow/disallow a particular bond.

F@H concerns itself with the molecules that make up the structures in the video.

Extremely fascinating. Please have a look!

And when done viewing the video, please consider downloading the F@H program and getting a protein to fold for yourself.

1 posted on 04/15/2007 7:39:50 PM PDT by texas booster
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To: 1066AD; 11Bush; A.Hun; abner; AbsoluteGrace; Advil; aft_lizard; ahayes; aliquando; ambrose; AMD; ...

New Folding thread ping!

This is a great video. While not connected to the Pande Group at Stanford, it is a state-of-the-art animation of actions within a cell.

Really worth a moment of your time!


2 posted on 04/15/2007 7:42:26 PM PDT by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120) Cure Alzheimers!)
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To: mastercylinder; Me; MediaMole; MeekOneGOP; melt; Michael K.; Mind-numbed Robot; MissyMa; ...

New Folding thread ping!

This is a great video. While not connected to the Pande Group at Stanford, it is a state-of-the-art animation of actions within a cell.

Really worth a moment of your time!


3 posted on 04/15/2007 7:44:20 PM PDT by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120) Cure Alzheimers!)
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To: texas booster
Wow!, it is like there is a entire universe going on within the cell in that simulation.

And most likely the simulation only touches the tip of the mountain.

4 posted on 04/15/2007 7:53:01 PM PDT by RunningWolf (2-1 Cav 1975)
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To: RunningWolf
Wow!, it is like there is a entire universe going on within the cell in that simulation.

The choreography and timing depicted in the cell are stunning, mindiboggling.

These are not random, chaotic, happenstance physical actions and reactions. This is a trillion cell dance of stupefying complexity and uncanny coordination.

5 posted on 04/15/2007 7:57:53 PM PDT by JCEccles
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To: texas booster
Those are some very interesting graphics but I was wondering: What language was used for the narration?

Some of the shorter words sounded very much like English. :=) It made me glad that I took up something as simple as computer programming.

6 posted on 04/15/2007 7:58:20 PM PDT by Bob
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To: texas booster
Folding@Home FAQ for new users:

What is Folding@Home?
A Stanford University project to find out how proteins fold.

Why it's important: Proteins folding wrong causes all kinds of diseases, like Alzheimer's, Parkinson's, and forms of cancer. Folding@Home uses novel computational methods and large scale distributed computing, to simulate timescales thousands to millions of times longer than previously achieved. Through Folding@home, scientists now have the horsepower to study the mechanics of protein folding. With its ability to share the workload among hundred of thousands of computers economically, Folding@home can help scientists understand how proteins snap, or don't, into their predestined shapes - and may help to explain the origins of diseases such as Alzheimer's and apparently unrelated diseases. We're fueling research that could end all that.


How does it work?: You download a safe, tested program (see link below) that is certified by Stanford University. It gets work from Stanford, runs calculations using your spare computer power, and sends the results back to the University.

Is it safe? Yes! Folding@Home rarely effects computer performance in any way and won't compromise your privacy in any way. It only uses the computing power you aren't using so it doesn't slow down other programs.


How do I get started folding for Team FreeRepublic?:
1.) Download the folding program from Stanford University's folding download page (Folding@home Client Download). Type in your desired username.
2.) Type in 36120 for the team number. THIS IS VERY IMPORTANT - if you get the number wrong, you won't be folding for team FreeRepublic!
3.) The third question asks, "Launch automatically at machine startup, installing this as a service?" - We recommend you answer YES. Otherwise you will have to manually start the program after every reboot.


How can my computer help? Even if they were given exclusive access to all of the world's supercomputers, Stanford still wouldn't have as much processing power as they get from the supercluster of people's desktop systems Folding@home relies on. Modern supercomputers are essentially a cluster of hundreds of processors linked by fast networking. But Stanford needed the power of hundreds of thousands of processors, not just hundreds.


There's no reason to not get involved! It's free, easy, and you can know you're helping every minute without lifting a finger.

*******************************************

List of Relevant Folding Links
Why Fold - Watch This !!


Another Folding Clip


The Inner Life of a Cell


Folding@home Client Download


FreeRepublic.com Folder Stats


Extreme Overclockers Stats for FreeRepublic


Another Stats Page


*******************************************
Competition (Not!!) Dummies ..Daily Kos


Dummie Folding Threads #7 #8 #9#10#11 #12


**************************************************
Other Useful Stuff - Links


How much are those work units worth? And what are they?
All Projects Listed
Point Summary for Workunits


Stat Image Generator


Fahmon Third Party Monitoring Software

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Past FreeRepublic Folding threads


#1 #2 #3 #4 #5 #6 #7 #8 #9 #10 #11 #12 #13 #14 #15 #16 #17 #18 #19 #20 #21 #22 #23 #24 #25 #26 #27 #28 #29 #30 #31 #32 #33 #34 #35 #36

7 posted on 04/15/2007 8:01:38 PM PDT by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120) Cure Alzheimers!)
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To: texas booster
Wow, that is really cool. I would love to have some staunch supporter of evolution explain how a cell just happened to come together in some primeval soup.
8 posted on 04/15/2007 8:01:43 PM PDT by notpoliticallycorewrecked (California : home of the fruits, nuts and flakes.)
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To: Bob
I was trying to explain folding to some friends and used this video to show proteins folding, the motor protein, etc.

I was hoping that they would react with glee at how wonderfully our bodies are made.

Lets just say that the eyes started glazing over with the first “leukocytes” and never unglazed.

I hope that FReepers will give it more of a chance, despite the language.

Or at least look at the pretty pictures ...

9 posted on 04/15/2007 8:10:03 PM PDT by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120) Cure Alzheimers!)
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To: notpoliticallycorewrecked

Bingo!

The deeper that we delve into the biology of life the more the mystery grows.

While I don’t have a time scale on the video, if there is one, most of these reactions occur in microseconds.

Millions of times in each cell, times trillions of cells in a body, times millions of seconds in a life, times the vast diversity of life that exists from a whale to an underwater bacteria living at the bottom of the ocean.

Its a little more than a coincidence.


10 posted on 04/15/2007 8:15:25 PM PDT by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120) Cure Alzheimers!)
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To: texas booster

Remember:

Mac, MacTel, PS3, Linux and Windows systems can all help us fold to make a difference!


11 posted on 04/15/2007 8:17:31 PM PDT by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120) Cure Alzheimers!)
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To: texas booster

Anybody here using the ATI streaming processor software for folding yet? WHen the new DAAMIT video cards come out I am switching to them seeing as nVidia drivers suck and I havent dared to fold yet on Vista but I do want to get back into the ‘fold’.


12 posted on 04/15/2007 8:18:55 PM PDT by aft_lizard (born conservative...I chose to be a republican)
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To: texas booster

Awesome video!


13 posted on 04/15/2007 8:22:34 PM PDT by alicewonders (I like Duncan Hunter for President in 2008!)
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To: alicewonders

36120 bump!


14 posted on 04/15/2007 8:24:53 PM PDT by Drango (A liberal's compassion is limited only by the size of someone else's wallet.)
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To: JCEccles
I hear you man!

And it is even more ‘of a clue’ than that.

There is not one of those processes that can be duplicated by any means (imperfect replication) outside of the cell.

Life itself is both an enigma, and a tribute to his glory.

15 posted on 04/15/2007 8:26:00 PM PDT by RunningWolf (2-1 Cav 1975)
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To: texas booster
Lets just say that the eyes started glazing over with the first “leukocytes” and never unglazed.

My eyes didn't glaze over but my ears did hurt a bit. :=)

The narration reminded me of a very old Rockwell spoof commercial. It was for their brand-new, highly cross-planarized, oscillating, self-resonant framistat or some such outlandish thing.

16 posted on 04/15/2007 8:28:00 PM PDT by Bob
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To: aft_lizard

IBM supposedly has an entire floor devoted to abusing the new processors, but they are not folding, just stress testing.

There is an active alpha program at Stanford testing the R600 series chips, and soon the integrated video chips will be tested.

Streaming teraflop-in-a-box DAMMIT chips are still several quarters away from reaching us, but the geeks that I talk to really think that they will leapfrog both NVidia and Intel.


17 posted on 04/15/2007 8:28:21 PM PDT by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120) Cure Alzheimers!)
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To: alicewonders

As good as the video is, it is even better to start folding on one of your systems.

Its not hard, and we WILL be here to help you get started.


18 posted on 04/15/2007 8:29:45 PM PDT by texas booster (Join FreeRepublic's Folding@Home team (Team # 36120) Cure Alzheimers!)
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To: notpoliticallycorewrecked
Well as you know, they wont explain it. They will make a personal assault on you instead in an attempt to shut you up.
19 posted on 04/15/2007 8:31:20 PM PDT by RunningWolf (2-1 Cav 1975)
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To: aft_lizard

Using a 1950 Pro to fold on one machine. It tends to do quite well (not quite the level of SMP, but not bad either). It seems the results from the ATI card almost match the point level of the PS3, and they can work on different proteins.

No matter what you fold on, it will do some good. A simple PC can fold virtually any protein type. SMP machines can also fold virtually any type and do so very quickly. Mac’s match the PC (single and smp) in their flexiblity (don’t have any of them though). ATI (GPU) and PS3 clients do specialized folding which is a bit more limited, but they do it very fast.

So it doesn’t really matter what you have, it will contribute and make the world a better place.

One important note: make sure you put 36120 as the team name (FR gets credit) and josephw as the username (I get credit - or use your own and take credit for yourself).

Remember everyone can help and we have consistently blown away the DU as we believe in charity and they are waiting for the govt to send them a cheque for a new system and monthly (welfare) payments to show their good will.


20 posted on 04/15/2007 8:32:13 PM PDT by JosephW (Mohammad Lied, People die!)
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