- Omar Abdel-Rahman - leader of the New York City landmark bomb plot
- Mahmud Abouhalima - involved in the 1993 World Trade Center bombing.
- Ahmad Mohammed Ajaj - involved in the 1993 World Trade Center bombing
- Mohamed Rashed Daoud Al-'Owhali - involved in the 1998 U.S. embassy bombings
- Mohammed Ali Hassan Al-Moayad - helped to finance al-Qaeda and Hamas
- Mirssa Araiza-Reyes - drug smuggler and undocumented alien; killed inmate Frank Melendez
- Nidal Ayyad - involved in the 1993 World Trade Center bombing
- Tyler Davis Bingham - Aryan Brotherhood member
- Maynard Campell - a 55 year old white separatist with ties to militia groups; was stabbed to death.
- Anthony "Gaspipe" Casso - Lucchese Crime Family figure and killer of at least 35 people
- Ibrahim Elgabrowny - involved in the New York City landmark bomb plot
- Wadih El Hage - involved in the 1998 U.S. embassy bombings
- Joey Estrella - convicted bank robber, killed in ADX Florence.
- Luis Felipe (a.k.a. King Blood) - Latin Kings gang leader
- Ronald Griesacker- Fraudster, passed $2 million in worthless checks. Released in 2002.
- Matthew F. Hale - White supremacist, (unsuccessfully) solicited the murder of federal judge Joan Lefkow
- Rodney Hambrick - serving a 68-year sentence on bomb charges
- Clement Rodney Hampton-Ell (a.k.a. Dr. Rashid) - involved in the New York City landmark bomb plot
- Robert Haney - bank robber
- Robert Hanssen- a former FBI agent serving life for spying for the U.S.S.R. for two decades
- Charles Harrelson - Mobster, father of actor Woody Harrelson
- Larry Hoover - Gangster Disciples gang leader
- Eyad Ismoil - involved in the 1993 World Trade Center bombing
- Anthony Jones - Multiple murderer
- Theodore Kaczynski - The Unabomber
- Yu Kikumura - member of the Japanese Red Army
- David Lane - Neo-Nazi leader, racketeering, conspiracy and violating the civil rights of radio talk show host Alan Berg
- Joseph Leissler - robber, murderer
- Raymond Luc Levasseur - American domestic bomber
- Tom Manning - Killed a New Jersey state trooper.
- Joseph Bryant McGee - bank robber
- Timothy James McVeigh (April 23, 1968 June 11, 2001), executed for Oklahoma City bombing
- Frank Melendez - a cocaine dealer from California killed in ADX Florence by Mirssa Araiza-Reyes.
- Barry Byron Mill - Aryan Brotherhood member
- Khalfan Khamis Mohamed - involved in the 1998 U.S. embassy bombings
- Dandeny Munoz-Mosquera - chief assassin for Pablo Escobar, responsible for the bombing of Avianca Flight 203
- Zacarias Moussaoui - Convicted for the September 11, 2001 attacks and sentenced to 6 life terms without parole in ADX Florence [1]
- Abdul Hakim Murad - involved in Operation Bojinka
- Terry Nichols - involved in the Oklahoma City bombing
- El Sayyid Nosair - involved in the 1993 World Trade Center bombing
- Raymond Oechsle - was incarcerated with Casso from 2001 to 2002 at ADX.
- Richard Reid - The "Shoe Bomber"
- Ahmed Ressam - serving 23 years for attempting to blow up Los Angeles International Airport
- Omar Mohammed Rezaq - Hijacked an Air Egypt flight in Greece in 1985.
- Oscar Rivera - leader of the Armed Forces of National Liberation, a Puerto Rican terrorist group, for bombing 28 targets in the Chicago area. Received an additional 15-year sentence for an escape attempt (from another prison).
- Eric Robert Rudolph - Olympic Park Bomber
- Mohammed A. Salameh - involved in the 1993 World Trade Center bombing
Thomas Silverstein -- Bank robber and murderer; killed guard Merle Clutts in another facility.
- Mutulu Shakur- an acupuncturist turned self-professed freedom fighter for the group Republic of New Afrika, sentenced to 60 years for bank robbery, conspiracy and murder (during the robbery, a policeman and two guards were killed.) Stepfather of late rapper Tupac Shakur, brother of Assata Shakur
- Douglas Taylor - Leader of the 88 Skinheads
- Saxon Taylor - Skinhead leader
- Manuel Torrez - 64 year old inmate killed at the hands of other inmates, the first in Supermax history.[2][3]
- Earnest James Ujaama - tried to develop an al-Qaeda camp in Oregon
- David Vargas - Convicted Of - Drugs & Voluntary Manslaughter.
- Danny Weeks - kidnapper
- Ramzi Ahmed Yousef - terrorist, involved in the 1993 World Trade Center bombing and Operation
Say what?
Looks like an all male prison. Where will they put Mary McCarthy?