All levity aside, the Nagant M1895 revolver’s cylinder moved forward when firing and closed the cylinder-to-barrel gap. I’ve never seen a suppressor on one, but that would be a “quiet” revolver.
There is always an exception.
I played with Nagant revolvers a bit.
In spite of the "seal", there is significant gas leakage at the barrel/cylinder intersection.
Not nearly as much as in a regular revolver, but it dampened my enthusiasm for making a silenced revolver.
I think it could be done; but a manually operated repeater, such as the welrod, or the more current VP9, are probably better solutions.