Free Republic
Browse · Search
General/Chat
Topics · Post Article

From the writeup:

“It not only repairs the weakened signals between neurons, but also restores associative memory, one of the early abilities lost in Alzheimer's.“

Calcium alpha-ketoglutarate (CaAKG) is readily available as a supplement. You want the calcium form of AKG.

We make less of this as we age.

From the paper:

“Ca-AKG, a calcium derivative of AKG, has emerged as a promising compound with potential benefits for aging and neurodegenerative diseases (Asadi Shahmirzadi et al. 2020; Zhang et al. 2023). Our previous work demonstrated that Ca-AKG supplementation extends lifespan and improves healthspan in mice (Asadi Shahmirzadi et al. 2020). Compared to free AKG, Ca-AKG offers several advantages, including greater chemical stability and improved bioavailability. Ca-AKG is acidic and absorbed more slowly in the gastrointestinal tract, resulting in a gradual and sustained release into the bloodstream. This prolonged absorption profile enables Ca-AKG to maintain its biological effects over an extended period, potentially enhancing its overall efficacy. Furthermore, AKG is a charged molecule with limited ability to cross cell membranes (Wu et al. 2016). “

There are multiple newer approaches to attack Alzheimer’s Disease and/or dementia, including a low carb diet or forms of fasting, the Mediterranean Diet, and supplements I’ve recently posted on, which include ultra-low-dose lithium orotate, EGCG (green tea) with Vitamin B3/nicotinamide.

1 posted on 01/01/2026 4:12:42 PM PST by ConservativeMind
[ Post Reply | Private Reply | View Replies ]


To: Mazey; ckilmer; goodnesswins; Jane Long; jy8z; ProtectOurFreedom; matthew fuller; telescope115; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 01/01/2026 4:13:52 PM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 1 | View Replies ]

To: ConservativeMind
Two other recent studies of ways to help:

Lithium loss ignites Alzheimer's, but lithium compound can reverse disease in mice (Lithium orotate)

https://freerepublic.com/focus/f-chat/4334274/posts

This Vitamin And Tea Combo May Quickly Rejuvenate Aging Brain Cells

https://freerepublic.com/focus/f-chat/4333081/posts

3 posted on 01/01/2026 4:16:00 PM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 1 | View Replies ]

To: ConservativeMind

thank
you !

i need to study up on all these things before Alzheimers strikes

cheer


4 posted on 01/01/2026 4:16:29 PM PST by faithhopecharity ("Politicians aren't born, they're excreted." Marcus Tullius Cicero (106 to 43 BCE))
[ Post Reply | Private Reply | To 1 | View Replies ]

To: ConservativeMind

Some say the medical cabal already has cures for Alzheimer’s, cancer and other chronic illnesses.

That they’re not telling us about.


5 posted on 01/01/2026 4:25:55 PM PST by reasonisfaith (What are the personal implications if the Resurrection of Christ is a true event in history?)
[ Post Reply | Private Reply | To 1 | View Replies ]

To: ConservativeMind

Bkmk


9 posted on 01/01/2026 5:01:25 PM PST by sauropod
[ Post Reply | Private Reply | To 1 | View Replies ]

To: ConservativeMind

Notice that long, exotic-sounding metabolite contains the word “keto.”


10 posted on 01/01/2026 5:06:38 PM PST by Blurb2350 (posted from my 1500-watt blow dryer)
[ Post Reply | Private Reply | To 1 | View Replies ]

To: ConservativeMind

Placeholder post


12 posted on 01/01/2026 5:38:28 PM PST by Bob434 (Time flies like an arrow, fruit flies like a banana)
[ Post Reply | Private Reply | To 1 | View Replies ]

To: ConservativeMind

Bookmarked.


14 posted on 01/01/2026 7:21:20 PM PST by KittyKares
[ Post Reply | Private Reply | To 1 | View Replies ]

To: ConservativeMind

ping


15 posted on 01/01/2026 7:27:09 PM PST by butterdezillion
[ Post Reply | Private Reply | To 1 | View Replies ]

To: ConservativeMind

I always thought I could be an Alzheimer’s model, but my friends said I had lost my mind.


17 posted on 01/01/2026 8:33:18 PM PST by samiam5
[ Post Reply | Private Reply | To 1 | View Replies ]

To: ConservativeMind

I notice that some brands add Vitamin C in the form of Calcium Ascorbate to the AKG Supplement. Is that the same as Calcium alpha-ketoglutarate (CaAKG)?


21 posted on 01/02/2026 7:41:10 AM PST by tired&retired (Blessings )
[ Post Reply | Private Reply | To 1 | View Replies ]

Free Republic
Browse · Search
General/Chat
Topics · Post Article


FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson