In the fictional TV series I wrote earlier about, the ship that had been sunk by the British had civilians traveling on board it. Many were the families of the officers. It was part of 3-4 other ships traveling together. I don’t know what the policy was of civilians being on these galleons, but I wonder if any of the individuals, of the 600 that were supposed to be on the ship at the time it was sunk, could have been civilians. Wikipedia, nor any of the other articles I’ve looked at, mention that possibility.
The Spanish Armada shipsAbout a century and a half earlier, they only have the crew and soldier numbers by squadron, but considerably smaller. I assume there's an original source for the 600 number.
BTW the Santa Ana listed on the Biscay squadron was the Santa And de San Jose referred to that way as there were 4 Santa Anas on the expedition.