Your understanding of the process of food getting into the body is a bit off.
Our intestines directly pass nutrients into our circulatory system (blood). There is nothing that routes to the liver over all the other organs, first.
https://www.niddk.nih.gov/health-information/digestive-diseases/digestive-system-how-it-works
From Pub Med.
The article doesn’t specify the percentage of food/drugs grabbed by liver first but it’s substantial.
Mistletoe, vitamin C, quercetin are dripped intravenously over hours to bypass intestine and liver.