Just because we don't find ET doesn't mean there isn't life.
Reminds me of an old Star Trek episode, on which they discovered silicon based life on a planet they visited.
The main storyline was that the living creature they discovered was silicon based and not carbon based, as the assumption had been that life as we know it is carbon based.
So, while life as we know it is carbon based, what if there is life as we don’t know it out there somewhere????