Mice are a convenient mammalian model, but they have their limitations.
Could we cool it on the Big Pharma cabal that withholds cures? There are a lot of unknown unknowns, i.e. the investigators don't know what they are still ignorant about. A lot of basic biomedical science has yet to be done. There are a lot of physicians involved who want to provide cures, who would consider withholding cures unethical, and who have jumbo egos.
It’s not the physicians that are the problem.
The big money is not in individual effort, but in selling snake oil at high prices to those physicians and their patients.