Carried one on the 5km zone on our side of the *Iron Curtain* fences in Germany in the 1960s and taught the NATO weapons familiarization course to Seventh Army NCO Academy troops at Bad Toelz. Had one when I was in Israel but mostly carried a Browning GP instead, and had one as my ambush answer while driving a Toyota half-ton truck or Volkswagen Rabbit in Africa in the '70s- the Uzi fit very nicely in the full-dash-width package shelf the Rabbit had instead of a glove box. Very neat, but not much reach- and now not often seen in Israel, where most in the Army carry M16s, and the police reservists [mishmir esrachi] mostly carry old US M1 carbines- more reach.
Mine didn't care much for US jacketed hollowpoint ammo, which would be what I'd want to use inside a home. But that was easy to fix, and in a vehicle in the outdoors with ball ammo mixed with occasional spits of three tracers, very nice.
Not much reach needed for home defense unless you're anticipating a visit from a gang (like the "HRT" and then it would be best to mine the place and leave before they get there :-) Biggest problem is cost. I paid $2800 + $200 fedtax for mine about 10 years ago, but they're running about $7000 now I hear. Mine eats Norinco ammo just fine.