I currently have VS2k8, Vmware Workstation with 2 to 4 VMs running, multiple custom apps, Excel 2k7, Outlook 2k7, Firefox 3 and IE 7 running with zero threading issues.
CPU utilization has been 80/75/60 averaged over the past 30 minutes.
Good for you. Now, whatever you do, don’t try and load any Adobe apps, printer drivers that Vista doesn’t automatically find, or connect to Novell or Unix/Linux resources.