I've even seen what happens when a boards thermal overheat protection system fails. Some of the testing we do uses sealed temp controlled chambers. If the cooling compressor moderation circuit fails, the heat from the board running will accumulate. It'll get hot enough to melt the solder holding the parts on to the board, delaminate the board itself, and cause all the insulation to drip off the wires.
Icky looking stuff... ;-)
Wow! I've never seen a board melt before. I've had a computer start on fire where I used to work once while I was trying to fix it, but it didn't melt the motherboards.