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Keyword: type1diabetes

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  • Immune systems of type 1 diabetics can be ‘retrained’ to stop destroying insulin, scientists show

    08/10/2017 7:54:32 AM PDT · by Red Badger · 12 replies ^ | 9 August 2017 | Sarah Knapton, Science Editor
    The damaged immune systems of diabetics can be ‘retrained’ to stop them destroying insulin, scientists believe, following successful trials of a pioneering new therapy. Researchers at King’s College London and Cardiff University showed that injecting patients with tiny protein fragments prevented immune cells from targeting vital insulin. Type 1 diabetes develops when a patient's immune system mistakenly attacks the insulin producing beta cells in the pancreas. Without treatment the number of beta cells will slowly decrease and the body will no longer be able to maintain normal blood sugar (blood glucose) levels, leading to patients needing daily injections. But a...
  • Type 1 Diabetes Breakthrough with Artemisinin Treatment

    12/05/2016 7:18:10 AM PST · by posterchild · 7 replies
    The Diabetic News ^ | Dec 3, 2016
    Researchers have announced that FDA-approved artemisinins, used for decades to treat malaria, offer a completely new therapy for type 1 diabetes. It promises to be a simple and elegant strategy to heal diabetes type 1: Replacing the destroyed beta-cells in the bodies of patients with newly-produced insulin-secreting cells. For years, researchers around the world tried various approaches with stem- or adult cells in order to induce this transformation. Their effort lead to a fundamental understanding of the molecular mechanisms involved in the development of beta cells – however, a compound capable of doing the trick was missing
  • First Patient in Diabetes Trial is now Diabetes-Free

    03/25/2016 2:35:02 PM PDT · by Lizavetta · 33 replies
    True Activist ^ | 3/16/16 | Brianna Acuesta
    In a new clinical trial to observe a new method of injecting islet cells into a patient with Type 1 diabetes, doctors from the University of Miami’s Diabetes Research Institute have confirmed that their first trial patient no longer needs insulin therapy. Wendy Peacock, their first patient, has been giving herself insulin injections and following a strict daily schedule to take care of her diabetes since she was diagnosed with Type 1 diabetes at 17. Now 43, Peacock has undergone the surgery in this new trial and no longer needs injections because her body is producing insulin naturally. Since the...
  • NBC News comes to Cochise County

    05/18/2015 6:18:34 AM PDT · by SandRat · 3 replies
    Sierra Vista Herald ^ | Robert Charette
    The Chiricahua Community Health Center’s mobile clinic has been a boon for the region in recent years since it’s designed to treat rural and low income areas like those found in Cochise County. The clincs are empowered by grants from the national Children’s Health Fund, which made possible the story that NBC News will tell the world this week about Buena rising sophomore Efrain Gonzalez II. The mobile clinic treats Gonzalez for Type 1 Diabetes, which allows him to backpaddle into pass coverage just like any other defender in one of the Colts’ last football practices of the school year.
  • Possible Cure for Type 1 Diabetes Announced

    08/31/2014 1:18:08 PM PDT · by nickcarraway · 34 replies
    Daily Call ^ | August 30. 2014 | Jennifer Runyon
    I know this is a loaded and extremely controversial topic but there’s been a big break in the diabetes world. I thought it needed to be shared because no matter how you feel, it’s a big deal! ViaCyte Inc. has been given FDA approval to begin clinical trials on beta cell encapsulation. You may be wondering why this is a big deal. You see, in Type 1 diabetes the body’s own immune system attacks beta cells found in the pancreas. These beta cells produce insulin and the attack makes them unable to do that. Because the body can no longer...
  • Skin drug shows 'promising' results on type 1 diabetes

    09/22/2013 5:14:00 PM PDT · by Innovative · 4 replies
    BBC ^ | Sept 22, 2013 | BBC
    A drug that was used to treat a skin disorder has shown signs of being able to treat aspects of type 1 diabetes. A small trial on US patients suggests that alefacept helps the body produce its own insulin, which is key for people with type 1 diabetes.
  • Key Protein Accelerates Diabetes in Two Ways

    08/28/2013 1:27:20 PM PDT · by neverdem · 20 replies
    ScienceDaily ^ | Aug. 25, 2013 | NA
    The same protein tells beta cells in the pancreas to stop making insulin and then to self-destruct as diabetes worsens, according to a University of Alabama at Birmingham (UAB) study published online today in the journal Nature Medicine. Specifically, the research revealed that a protein called TXNIP controls the ability of beta cells to make insulin, the hormone that regulates blood-sugar levels. "We spent years confirming that TXNIP drives beta-cell death in both Type 1 and Type 2 diabetes," said Anath Shalev, M.D., director of the UAB Comprehensive Diabetes Center and senior author of the paper. "We were astounded to...
  • One Step Forward for DIY Health Care (Walter Russell Mead)

    08/22/2013 7:08:06 AM PDT · by neverdem · 3 replies
    The American Interest ^ | August 14, 2013 | Walter Russell Mead
    The California Supreme Court has ruled that public schools can give insulin injections to students without bringing in nurses. Prior to the ruling, some schools in the state required that shots only be given by licensed professionals, but the skewed nurse-to-student ratio was hampering children’s ability to get routine care. Parents with diabetic children sued for relaxed standards, and in the higher court, they won. LA Times: Laura Mecoy, mother of two teenagers with diabetes and a Los Angeles board member of a diabetes foundation, said the ruling “delivered a wonderful back-to-school present to our children.”“As a working parent, I...
  • Insulin Pumps Better Than Injections for Kids With Type 1 Diabetes: Study

    08/21/2013 8:35:55 PM PDT · by neverdem · 2 replies
    Over a median of 3.5 years, the devices worked better at controlling blood sugar, researchers say Devices called insulin pumps may work better at controlling blood sugar in children with type 1 diabetes than insulin injections, a new study finds. They might also cause fewer complications, the Australian researchers said. "This is the largest study of insulin-pump use in children," wrote a team led by Dr. Elizabeth Davis of the Princess Margaret Hospital for Children in Perth. "It also has the longest follow-up period of any study of insulin-pump therapy in children. Our data confirm that insulin-pump therapy provides an...
  • Interspecies Transplant Paves the Way for Diabetes Therapy

    07/20/2013 1:38:27 PM PDT · by neverdem · 24 replies
    Voice of America ^ | July 20, 2013 | Jessica Berman
    Researchers have come closer to the “Holy Grail” of treatment for people with type 1 diabetes. They have successfully transplanted insulin-producing islet cells from one species into another without the use of immunity-suppressing drugs. In the future this could provide an unlimited supply of tissue to treat people whose bodies cannot produce insulin. Insulin is a hormone produced by the pancreas that delivers glucose - a form of sugar that the body uses for fuel - to cells for energy. Since the immune systems of people with type 1 diabetes attack and destroy the islet cells that produce insulin, many...
  • What and when babies first eat may affect diabetes risk

    07/13/2013 7:05:27 PM PDT · by neverdem · 6 replies
    Science News ^ | July 11, 2013 | Nathan Seppa
    Children predisposed to type 1 diabetes are better off waiting until 4 months of age to consume solid foods Infants at risk of type 1 diabetes who receive their first solid foods between ages 4 months and 6 months appear less likely to develop the condition than others given solid food before or after that time window, a new study finds. Type 1 diabetes, which can strike children at any age, occurs when an aberrant immune reaction kills cells in the pancreas, requiring a person to take insulin shots. Two studies in 2003 found an association between early first foods...
  • New Type 1 diabetes vaccine shows promising results

    06/27/2013 3:53:11 PM PDT · by neverdem · 4 replies
    CBS News ^ | June 27, 2013 | MICHELLE CASTILLO
    A clinical trial for a Type 1 diabetes vaccine has resulted in promising findings, suggesting there may be a future where we can prevent people from getting the disease. Researchers completed a 12-week trial on a DNA-based vaccine on 80 subjects with Type 1 diabetes. The patients were able to maintain levels of a blood-borne intermediary that can stimulate insulin production, and some subjects were able to increase levels. That suggests the cellular changes that occur in patients with Type 1 diabetes may be shut down.  "We're very excited by these results, which suggest that the immunologist's dream of shutting...
  • Doctors make progress toward ‘artificial pancreas’

    06/23/2013 5:28:26 AM PDT · by Olog-hai · 3 replies
    Associated Press ^ | Jun 22, 2013 4:45 PM EDT | Marilynn Marchione
    Doctors are reporting a major step toward an “artificial pancreas,” a device that would constantly monitor blood sugar in people with diabetes and automatically supply insulin as needed. A key component of such a system—an insulin pump programmed to shut down if blood sugar dips too low while people are sleeping—worked as intended in a three-month study of 247 patients. This “smart pump,” made by Minneapolis-based Medtronic Inc., is already sold in Europe, and the U.S. Food and Drug Administration is reviewing it now. Whether it also can be programmed to mimic a real pancreas and constantly adjust insulin based...
  • Immune Protein Could Stop Diabetes in Its Tracks, Discovery Suggests

    05/30/2013 5:06:32 PM PDT · by neverdem · 7 replies
    ScienceDaily ^ | May 20, 2013 | NA
    Melbourne researchers have identified an immune protein that has the potential to stop or reverse the development of type 1 diabetes in its early stages, before insulin-producing cells have been destroyed. The discovery has wider repercussions, as the protein is responsible for protecting the body against excessive immune responses, and could be used to treat, or even prevent, other immune disorders such as multiple sclerosis and rheumatoid arthritis. Professor Len Harrison, Dr Esther Bandala-Sanchez and Dr Yuxia Zhang led the research team from the Walter and Eliza Hall Institute's Molecular Medicine division that identified the immune protein CD52 as responsible...
  • Biomaterial Shows Promise for Type 1 Diabetes Treatment

    05/13/2013 11:43:36 PM PDT · by neverdem · 5 replies
    ScienceDaily ^ | May 9, 2013 | NA
    Researchers have made a significant first step with newly engineered biomaterials for cell transplantation that could help lead to a possible cure for Type 1 diabetes, which affects about 3 million Americans. Georgia Tech engineers and Emory University clinicians have successfully engrafted insulin-producing cells into a diabetic mouse model, reversing diabetic symptoms in the animal in as little as 10 days. The research team engineered a biomaterial to protect the cluster of insulin-producing cells -- donor pancreatic islets -- during injection. The material also contains proteins to foster blood vessel formation that allow the cells to successfully graft, survive and...
  • Global Surge in Type 1 Diabetes Still an Enigma

    03/27/2013 11:47:37 PM PDT · by neverdem · 16 replies
    Everyday Health ^ | March 22, 2013 | Johannah Sakimura
    Though theories abound, scientists still don't understand what is causing the rise in type 1 diabetes in children worldwide. The incidence of type 1 diabetes in children is on the rise worldwide, with the number of new cases growing by an average of 3% per year in youth under age 15. The reasons for the sharp increase remain a medical mystery, since researchers have not been able to identify the changing conditions that are causing more kids to be diagnosed in recent decades. A new study presented this week at the annual Society for Endocrinology conference may help shed more light...
  • Diabetes Reversal In Mice Via Stem Cells

    03/07/2013 3:15:32 PM PST · by neverdem · 18 replies
    redOrbit ^ | June 28, 2012 | Connie K. Ho
    Diabetes is a detrimental disease. In order to combat the illness, University of British Columbia (UBC) researchers conducted a study with an industry partner and discovered that stem cells can reverse Type 1 diabetes in mice. The discovery leads the way for the development of innovative treatments of diabetes, which is caused by deficient production of insulin by the pancreas. Insulin allows glucose to be held by the bodyÂ’s muscle, fat, and liver; in turn, itÂ’s used as fuel for the body. Blindness, heart attack, kidney failure, nerve damage, and stroke are possible consequences of low insulin production. The research...
  • Vitamin D deficiency linked to Type 1 diabetes

    11/27/2012 11:24:52 AM PST · by neverdem · 28 replies
    Science Codex ^ | November 15, 2012 | NA
    A study led by researchers from the University of California, San Diego School of Medicine has found a correlation between vitamin D3 serum levels and subsequent incidence of Type 1 diabetes. The six-year study of blood levels of nearly 2,000 individuals suggests a preventive role for vitamin D3 in this disease. The research appears the December issue of Diabetologia, a publication of the European Association for the Study of Diabetes (EASD). "Previous studies proposed the existence of an association between vitamin D deficiency and risk of and Type 1 diabetes, but this is the first time that the theory has...
  • Study: 1 in 4 kids diabetic or pre-diabetic

    05/21/2012 10:06:13 PM PDT · by neverdem · 20 replies
    KFVS (CAPE GIRARDEAU, MO) ^ | May 21, 2012 | Christy Millweard
    CAPE GIRARDEAU, MO (KFVS) - Recent data shows a shocking jump in youth diabetes. A new study in the Journal of the American Academy of Pediatrics said 1 out of 4 youth in the U.S. is diabetic or pre-diabetic. The study looked at kids under 20 years old. It showed between 2000 and 2008, the percentage of teens with pre-diabetes and diabetes jumped from nine to 23 percent. Local Diabetes Educator Janet Stewart at Southeast Health said in the past decade she's seen the number of kids with Type 1 or Type 2 diabetes jump almost 30 percent. She said...
  • Scientists Shed New Light On Link Between 'Killer Cells' and Diabetes

    01/16/2012 9:04:30 PM PST · by neverdem · 18 replies
    ScienceDaily ^ | Jan. 15, 2012 | NA
    Killer T-cells in the human body which help protect us from disease can inadvertently destroy cells that produce insulin, new research has uncovered. The study provides the first evidence of this mechanism in action and could offer new understanding of the cause of Type 1 diabetes. Professor Andy Sewell, an expert in human T-cells from Cardiff University's School of Medicine worked alongside diabetes experts from King's College London to better understand the role of T-cells in the development of Type 1 diabetes. The team isolated a T-cell from a patient with Type 1 diabetes to view a unique molecular interaction...