Free Republic

UCLA/VA Study Finds Chemical Found in Curry May Help Immune System Clear Amyloid Plaques Found in Alzheimer’s Disease UCLA/VA researchers found that curcumin — a chemical found in curry and turmeric — may help the immune system clear the brain of amyloid beta, which form the plaques found in Alzheimer's disease. Published in the Oct. 9 issue of the Journal of Alzheimer's Disease, the early laboratory findings may lead to a new approach in treating Alzheimer's disease by enhancing the natural function of the immune system using curcumin, known for its anti-inflammatory and anti-oxidant properties. Using blood samples from six...

The unorthodox practice of chelation No one knows for certain what causes autism, but one theory has ignited an intense debate Autism is a mysterious and devastating disorder that is believed to affect as many as 500,000 children in this country. No one knows for certain what causes autism, but one theory — chelation— has sparked controversy. Now, Jim Adams wants to put that theory to the test. In a desperate quest for answers, he is using his scientific know-how to test a controversial therapy called "chelation." And he has a special reason for taking on this mission — his...

PROBIOTIC bacteria given to autistic children improved their concentration and behaviour so much that medical trials collapsed because parents refused to accept placebos, a scientist revealed yesterday. The effect of the bacteria was so pronounced that some of the parents taking part in what was supposed to be a blind trial realised their children were taking something other than a placebo. A number then refused to give their children the placebo when they were due to switch, resulting in the collapse of the trial. Glenn Gibson, a microbiologist who ran the study of 40 autistic children aged between four and...

Children with autism have a abnormal metabolic profile that may play a role in the condition, according to researchers at the University of Arkansas. The researchers believe autistic children are more vulnerable to oxidative stress, which occurs when the antioxidant system fails to counteract the production or exposure to free radicals. These free radicals then damage cells in the brain, as well as the gastrointestinal tract, and the immune system, which they believe may contribute to the the neurological, gastrointestinal and immunologic pathology that occurs in autistic children. The team analyzed and compared blood samples from 95 autistic children with...

BOSTON (Reuters Health) - Use of echinacea, or extract of the purple coneflower, before the onset of full-blown symptoms of the common cold reduces the incidence by more than a half and the duration by almost two full days, researchers reported here at the annual meeting of the American College of Clinical Pharmacology. There are approximately one billion colds reported annually, Dr. Sachin A. Shah told meeting attendees. He commented that 20 percent of patients report using nutraceuticals for symptom management. Of these, echinacea is the most commonly used. Shah of the University of Connecticut, Storrs and colleagues conducted a...

PHILADELPHIA -- Consumption of Vitamin D tablets was found to cut the risk of pancreatic cancer nearly in half, according to a study led by researchers at Northwestern and Harvard universities. The findings point to Vitamin D's potential to prevent the disease, and is one of the first known studies to use a large-scale epidemiological survey to examine the relationship between the nutrient and cancer of the pancreas. The study, led by Halcyon Skinner, Ph.D., of Northwestern, appears in the September issue of Cancer Epidemiology Biomarkers & Prevention. The study examined data from two large, long-term health surveys and found...

Silibinin, a drug derived from milk thistle, destroys lung cancer in mice, investigators at the University of Colorado, Denver report in the Journal of the National Cancer Institute. Lead investigator Dr. Rana P. Singh told Reuters Health, "We have been studying milk thistle components, silymarin and silibinin, to examine their efficacy and mechanisms against different...cancers for over a decade." In the current study, Singh's team injected mice with a chemical called urethane to induce lung cancer. The animals then received diets containing different doses of silibinin. "We obtained pure silibinin from Sigma Chemical Co., and silibinin diets were commercially prepared...

Drinking fruit and vegetable juices more than three times a week can dramatically cut the chances of developing Alzheimer's disease, a new study has found. Researchers followed almost 2,000 volunteers for up to 10 years while monitoring their juice consumption and brain function. They found the risk of Alzheimer's was 76 per cent lower for those who drank juices more than three times a week compared to those who drank them less than once a week. Other research has shown that eating curry can help stave off the disease and improve mental agility because of compounds found in the spice...

LOWELL – For those who think that apple juice is a kid’s drink, think again. Apples and apple juice may be among the best foods that baby boomers and senior citizens could add to their diet, according to new research that demonstrates how apple products can help boost brain function similar to medication.  Animal research from the University of Massachusetts Lowell (UML) indicates that apple juice consumption may actually increase the production in the brain of the essential neurotransmitter acetylcholine, resulting in improved memory.Neurotransmitters such as acetylcholine are chemicals released from nerve cells that transmit messages to other nerve cells. ...

Hopkins study shows combination of curcumin and quercetin greatly reduces size and number of colorectal polyps A small but informative clinical trial by Johns Hopkins investigators shows that a pill combining chemicals found in turmeric, a spice used in curries, and onions reduces both the size and number of precancerous lesions in the human intestinal tract. In the study, published in the August issue of Clinical Gastroenterology and Hepatology, five patients with an inherited form of precancerous polyps in the lower bowel known as familial adenomatous polyposis (FAP) were treated with regular doses of curcumin (the chemical found in turmeric)...

WASHINGTON (Reuters) - Cancer researchers urged people on Wednesday to take more vitamin D to lower their risk of colon, breast and ovarian cancer, saying studies showed a clear link. "Our suggestion is for people to increase their intake," through diet or a vitamin supplement, Dr. Cedric Garland said in a telephone interview. Garland's research team reviewed 63 studies, including several large long-term ones, on the relationship between vitamin D and certain types of cancer worldwide between 1966 and 2004. He said the benefit of vitamin D was as clear as the harmful link between smoking and lung cancer. "There's...

Anyone concerned about their bones is likely to make sure they have plenty of vitamin D, either by getting enough sunshine, eating fish, or taking supplements. Yet scientists know surprisingly little about how the compound works. A new study has finally shed some light on this process, showing how the vitamin takes part in a delicate balancing act between cells that tear down our bones and cells that rebuild them. Vitamin D is a familiar player in bone health. Without sufficient amounts of this hormone, our frames become frail with disorders such as osteoporosis or rickets. But vitamin D has...

Cancer Cell Biology Vitamin E succinate suppresses prostate tumor growth by inducing apoptosis Mokenge P. Malafa 1 *, Frida D. Fokum 2, Jennifer Andoh 2, Leslie T. Neitzel 2, Sucharita Bandyopadhyay 3, Rui Zhan 3, Megumi Iiizumi 3, Eiji Furuta 3, Elizabeth Horvath 1, Kounosuke Watabe 3 1Division of GI Tumors, Department of Interdisciplinary Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL2Surgical Oncology Laboratory, Department of Surgery, Southern Illinois University School of Medicine, Springfield, IL3Department of Medical Microbiology and Immunology, Southern Illinois University School of Medicine, Springfield, IL email: Mokenge P. Malafa (malafamp@moffitt.usf.edu) *Correspondence to Mokenge P....

Australian researchers have discovered that fish oil rich in omega 3 and 6 fatty acids may improve attention spans and even help children with ADHD. Children with behavioural problems can seem like little terrors. But according to doctors, they are not problem kids: they are sick kids.   Experts have long debated whether or not attention deficit hyperactivity disorder (ADHD) even exists, let alone an effective treatment or cure. But a new study has claimed results. Researchers at the University of South Australia and CSIRO studied 145 children with ADHD, giving some capsules containing fish oil high in omega 3 and...

Capsaicin, the compound that gives red pepper its heat, could stop the spread of prostate cancer, claims a new study. Red chilli pepper has previously been linked to inhibiting the growth of pancreatic cancer cells, and has been suggested to cut fat and energy intake when added to the diet. “We show that capsaicin has a profound inhibiting effect on the growth of prostate cancer cells in vitro and in vivo , inducing apoptosis [programmed cell death] of prostate cancer cell lines,” wrote lead author Akio Mori from the University of California, Los Angeles. The new study, published in the...

I'm sitting here sipping a bottle of Bossa Nova açai (pronounced ah-sigh-ee) juice, which according to the label is "nature's healthiest, highest antioxidant fruit. "The "original" and "pure" juice is sweetened with agave, a kind of cactus. It's hard to describe the taste: a little like pomegranates and blueberries, with a touch of pear. It's good and I will definitely drink it again, although I don't feel any compulsion to rush back to the market to buy it.This isn't your father's Concord grape juice. Fruit juices now come with scientific data printed right on the bottle! This one has a...

Turmeric may reduce leukaemia risk - expert September 09 2004 at 04:22PM London - Turmeric, a spice used extensively in Asia as a key ingredient of curry, may be protecting children against leukaemia, a scientist said on Thursday. Rates of the blood cancer have been rising steadily for the past 50 years but its incidence in Asia is much lower than in the West. Professor Moolky Nagabhushan, of the Loyola University Medical Centre in Chicago, told a conference that factor could be due, at least partly, to turmeric. "Some of the known risk factors that contribute to the high incidence...

Broccoli, cabbage, cauliflower: the vegetables that may prevent cancer · Foods contain chemicals that help repair DNA· Study backs link between diet and disease Ian Sample, science correspondent Wednesday February 8, 2006 The Guardian (UK) Natural chemicals found in soya beans and vegetables such as broccoli, cabbage and cauliflower boost the body's ability to repair damaged DNA and may prevent cells turning cancerous, scientists said yesterday. Studies have suggested that eating vegetables appears to provide some protection against certain cancers, but until now the reason why has been a mystery. Researchers at Georgetown University in Washington DC believe the answer...

Ladies, if you love your man, give him cauliflower curry with a side of kale for dinner. It may stave off prostate cancer, according to research released yesterday by Rutgers University. Though they don't often make the favorite menus of most men, cauliflower and kale -- along with cabbage, broccoli, brussels sprouts, kohlrabi, watercress and turnips -- contain a chemical that is a significant cancer-preventive.

Eating carrots, which are rich in the nutrient beta carotene, as well as foods containing the antioxidant vitamins C and E and zinc, results in a significantly reduced risk of age-related macular degeneration in elderly people, a new Dutch study has found. Currently, age-related macular degeneration affects 11.5 percent of white people over the age of 80. The number of people severely disabled by late-stage AMD in the United States is expected to increase by more than 50 percent, to 3 million, in the next 20 years. Previous studies evaluating antioxidants had shown conflicting results, with one major study showing...

Breathing Easier with Vitamin D Janet Raloff Most people associate vitamin D, the sunshine vitamin, with strong bones. But studies in the past few years have linked this essential nutrient to a bonanza of additional benefits—from fighting cancer and diabetes to strengthening muscles. Physicians in New Zealand have now linked the vitamin to yet one more apparent advantage: improved lung function. Peter N. Black is a University of Auckland internist with a research interest in chronic obstructive pulmonary disease (COPD)—a category including diseases most people know as emphysema and chronic bronchitis. Classic signs of COPD are holes in lung tissue...

The nude mouse tale: Omega-3 fats save the life of a terminal cancer patient Category: Cancer/Oncology News Article Date: 11 Nov 2005 Ron Pardini is not a medical doctor. Yet he is seen as a hero by his cancer-stricken neighbor, "D.H." Pardini helped the 78-year-old after D.H. was diagnosed with terminal lung cancer. "In 2000 he was told by his doctor he had only a few months to live," said Pardini, a professor of biochemistry and associate director of the Nevada Agricultural Experiment Station at the University of Nevada, Reno. "But five years later, he is still alive, and has...

A combination of vitamin D and an over-the-counter painkiller halts the growth of prostate cancer cells, researchers at Stanford University report.Although their work was done with cells grown in the laboratory, the results were so promising that a trial of the treatment has been started with prostate cancer patients, said Dr. David Feldman, a professor of medicine at Stanford and lead author of the study in the Sept. 1 issue of Cancer Research. The trial used calcitriol, a form of vitamin D available only by prescription, and naproxen, sold over the counter as Aleve and other brand names. The original...

Ginseng can help keep you clear of colds, say scientists By Nic Fleming, Science Correspondent (Filed: 25/10/2005) People who take ginseng suffer substantially fewer colds, research published yesterday showed. Only one in 10 of those given daily doses of North American ginseng root extract suffered two or more colds during four months including winter, compared with almost a quarter of those taking placebos. While a range of health benefits have been claimed for the herb, including combating flu and colds, many previous attempts to test such claims scientifically have been of poor quality. Publication of the research in the Canadian...

By Greg Arnold, DC, CSCS, October 19, 2005, abstracted from “Anticancer properties of propofol-docosahexaenoate and propofol-eicosapentaenoate on breast cancer cells” in the June 7, 2005 issue of Breast Cancer Research   Despite increases in technology, research, and education, breast cancer incidence in the U.S. has increased from one in twenty people in 1960 to one in eight today, with a woman being diagnosed every three minutes. In addition to the 216,000 new cases of invasive breast cancer expected to be diagnosed in 2004, 59,390 new cases of non-invasive breast cancer will be diagnosed, both expected to claim the lives of...

CHICAGO (Reuters) - Eating fish at least once a week slows the toll aging takes on the brain, while obesity at midlife doubles the risk of dementia, a pair of studies concluded on Monday. Omega-3 fatty acids contained in fish have been shown to boost brain functioning as well as cutting the risk of stroke, and eating fish regularly appears to protect the brain as people age, the six-year study of Chicago residents said. "The rate of (mental) decline was reduced by 10 percent to 13 percent per year among persons who consumed one or more fish meals per week...

SACRAMENTO - Nearing the end of their 2005 session, California legislators approved bills Thursday to allow illegal immigrants to have driver's licenses and to keep certain nutritional supplements out of the hands of student athletes. Among the dozens of measures awaiting final votes were bills that would bar the sale or rental of extremely violent video games to minors, allow schools to use alternatives to the high school graduation exam and promote a massive expansion of solar energy use.That bill, by Sen. Kevin Murray, D-Culver City, would offer subsidies to home and business owners that install solar panels. It was...

High dose vitamin E supplementation extends median and maximum lifespan in mouse studyA report published online in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology (http://ajpregu.physiology.org/) revealed the findings of researchers from the University of Cadiz in Spain and the University of Buenos Aires in Argentina that feeding mice high doses of vitamin E increased lifespan and improved neurological performance. Professor Alberto Boveris of the University of Buenos Aires and colleagues used a senescence accelerated strain of mice whose median lifespan is 60 to 70 weeks and whose maximum lifespan is 100 to 120 weeks. (Maximum lifespan is the...

A new study conducted by researchers at The University of California Irvine suggests that folates or B-vitamin nutrients found in oranges, legumes, leafy green vegetables and folic acid supplements are more effective in limiting Alzheimer's disease risk than antioxidants and other nutrients. The team led by Maria Corrada and Dr Claudia Kawas of UC Irvine's Institute for Brain Aging and Dementia analyzed the diets of non-demented men and women aged 60 and older. They compared the food nutrient and supplement intake of those who later developed Alzheimer's disease to the intake of those who did not develop the disease. "Although...

Preventing Alzheimer's disease may be as simple as increasing the amount of the B vitamin called folate that you get from fruits, green vegetables and supplements, researchers suggest in a new study. ADVERTISEMENT According to the study, older people whose folate intake is above the recommended dietary allowance are at a significantly reduced risk of developing Alzheimer's. However, the researchers cautioned that far more research is needed to establish a link between folate and the possible prevention of the brain-wasting disease. In fact, one previous study found folate encouraging the development of Alzheimer's disease. This latest study appears in the...

July 29, 2005 -- Whey may be good for more than just Little Miss Muffet. A new study shows adding whey to a high-carbohydrate meal may help people with diabetes keep their blood sugar levels under control. Researchers found drinking a whey supplement mixed with water along with a high glycemic index (GI) meal, like mashed potatoes with meatballs, prevented the dramatic spikes in blood sugar that normally occur in people with type 2 diabetes. Whey is a protein found in milk and is also available as a nutritional supplement. Researchers say the results suggest that whey aids in blood...

UIC Researchers Show How Cancer-preventing Foods Work Researchers at the University of Illinois at Chicago are unraveling the biochemical mechanism by which functional foods combat cancer."Compounds like sulforaphane in broccoli and resveratrol in wine have been shown to prevent cancer," said Andrew Mesecar, associate professor of pharmaceutical biotechnology in the UIC College of Pharmacy. "They do that by signaling our bodies to ramp up the production of proteins capable of preventing damage to our DNA."We now have a good idea how that signal works."The findings are published in this week's Early Edition of the Proceedings of the National Academy of...

SACRAMENTO — Gov. Arnold Schwarzenegger ended his $8-million contract with a muscle magazine publisher last week. But his deep emotional, political and business ties to bodybuilding — and to the supplement industry that feeds it — won't be so easily severed. Since becoming governor, Schwarzenegger has remained closely involved with the bodybuilding world and with the supplement companies whose products promise such things as ripped muscles, "thermonuclear" energy and better sex. According to documents and interviews with industry leaders, Schwarzenegger has continued to give the industry advice. He has participated in private meetings about government regulations. The governor also received...

Defeat CAFTA and save your supplements. You must ACT NOW! ACT NOW to preserve your access to nutrients, effective vitamins and minerals, and nutritional medicine! We have leverage - it's very close, perhaps within 1 vote! Listen to Len & Joe (Ask the Pharmacist Group) discuss why this is an important issue for all of us! CAFTA - BAD for jobs, small businesses, health stores, health freedom In the fine print the US is being signed up to global regulations that override US supplement laws. The outcome for CAFTA is up for grabs, as the vote is very close in...

THE MOSS REPORTS When it comes to maintaining health and fitness, we are all accustomed to the 'no pain, no gain' philosophy. We don't expect to be able to make significant improvements in our health without depriving ourselves of something or pushing ourselves perhaps beyond what is immediately comfortable. How refreshing, therefore, to discover that simply by eating something totally delicious we can also significantly improve our health and help build a defensive shield against cancer.This week I discuss some research that has demonstrated the extraordinary health benefits of berries, those colorful, delightful treats that are such an integral part...

SACRAMENTO (AP) - Gov. Arnold Schwarzenegger was criticized for having a conflict of interest last week after it was revealed he vetoed a bill regulating food supplements while he had a multimillion dollar contract with magazines that profit from the industry. In an interview with The Associated Press, the governor explained why he felt there was no conflict and said his support for the magazines and nutritional supplements dates to his earliest days as an aspiring body builder. "This has nothing to do with money," he said in a telephone interview Friday from Los Angeles. "Of course, for me, it...

SACRAMENTO — Two days before he was sworn into office, Gov. Arnold Schwarzenegger accepted a consulting job paying an estimated $8 million over five years to "further the business objectives" of a national publisher of health and bodybuilding magazines. The contract pays Schwarzenegger 1% of the magazines' advertising revenue, much of which comes from makers of nutritional supplements. Last year, the governor vetoed legislation that would have imposed government regulations on the supplement industry. According to records filed Wednesday with the Securities and Exchange Commission, Schwarzenegger entered into the agreement with a subsidiary of American Media Inc. on Nov. 15,...

SAN FRANCISCO (AP) - Tucked deep in the August 2005 issue of Muscle & Fitness magazine, past the photographs of men with chiseled muscles and stories such as "How I Built the World's Biggest Chest," is a glossy, two-page article proclaiming "It's Now Or Never!" The article details the bodybuilding industry's efforts to block state and federal regulations on nutritional supplements. It also proclaims the support of a powerful spokesman, California Gov. Arnold Schwarzenegger. The story describes how Schwarzenegger attended a private meeting with bodybuilding executives at the Arnold Classic in March to vow a united front in the battle...

SACRAMENTO (AP) - Gov. Arnold Schwarzenegger is being paid $1 million a year for his role as a consultant to a company that publishes several fitness magazines, a deal critics say represents a serious conflict of interest for the former bodybuilding champion. The payments, revealed Wednesday in filings with the U.S. Securities and Exchange Commission, are from Schwarzenegger's consulting job with American Media Operations, a subsidiary of the company that publishes Flex and Muscle & Fitness magazines, among others. Critics say the contract is a conflict of interest because Schwarzenegger's pay comes from the magazines' advertising revenue and the magazines...

Deepening his personal involvement in an industry that has business pending at the Capitol, Gov. Arnold Schwarzenegger earlier this year helped dietary supplement companies launch a lobbying group. An article in the August 2005 edition of Muscle & Fitness magazine, for which Schwarzenegger serves as executive editor, recounts his attendance at a March 5 meeting at which the lobbying group formed and says the governor remains "a phone call away" from the organization. The meeting took place while legislation was pending that would restrict high school athletes from using some performance-enhancing supplements. The bill still awaits action in the Legislature....

EU Limits Dietary Supplement Sales NewsMax.com Wires Tuesday, July 12, 2005 BRUSSELS, Belgium -- The European Union's high court upheld proposed restrictions on the sale of food supplements on Tuesday despite objections from trade organizations that claimed the rules would ban popular vitamin pills. The European Court of Justice said the EU law was "appropriate for securing the free movement of food supplements and ensuring the protection of human health."

High-dose folic acid pills — providing as much of the nutrient as 2.5 pounds of strawberries — might help slow the cognitive decline of aging. So says a Dutch study that's the first to show a vitamin could really improve memory. The research, unveiled Monday at a meeting of Alzheimer's researchers, adds to mounting evidence that a diet higher in folate is important for a variety of health effects. It's already proven to reduce birth defects, and research suggests it helps ward off heart disease and strokes, too. The new study doesn't show folic acid could prevent Alzheimer's — the...

Omega-3 supplements could help children with autism manage some of their symptoms, believe Scottish researchers, who have recorded a deficiency of certain fatty acids in autistic children. The researchers believe that higher levels of the enzyme phospholipase, seen in preliminary studies on blood samples from autistic children, may metabolise fatty acids in these children more quickly than in those without the condition. This could impact the levels of omega-3 fats like DHA and the omega-6 fatty acid ARA. Both are crucial to mental health, development and also fight off infection. The researchers at the universities of Stirling and Edinburgh have...

A combination of omega-3 fatty acids, found naturally in oily fish, and the anesthetic propofol appears effective in fighting breast cancer and may provide the basis for the development of new drugs to treat the disease, researchers report. In laboratory tests, this combination reduced the ability of breast cancer cells to turn into malignant tumors -- inhibiting cancer cell migration by 50 percent and greatly reducing their metastatic activity, the study said. Researchers at the Methodist Research Institute and Indiana University in Indianapolis studied the effects on breast cancer cells of two omega-3 fatty acids - docosahexaenoic acid (DHA) and...

FRIDAY, June 10 (HealthDay News) -- Cancer researchers have been given a million-dollar grant to investigate the therapeutic value of the folk medicine propolis and the food spice turmeric. The U.S. National Cancer Institute grant is earmarked for the study of the two alternative remedies, each of which has shown promise in reducing risks for breast, prostate and colorectal malignancies, and in enhancing cancer treatment. Propolis and turmeric are rich in plant polyphenolic compounds that exhibit potent antitumor activities, the researchers said. "A very interesting property of these compounds is that they have been shown to cause cell death in...

You might have heard rumors about the international rulemaking process known as Codex Alimentarius, or "Food Code". This July, food safety regulators from all over the world will meet in Rome to decide upon global guidelines for the vitamin and mineral trade. Support world health. Support access to dietary supplements Codex is a little-discussed process -- but one that is establishing the world's regulatory model for vitamins, minerals, and eventually all dietary supplements. TAKE ACTION! Promote health choice worldwide. Tell the U.S. Codex delegation and Congress to make our law, the Dietary Supplement Health and Education Act (DSHEA), the international...

Fatty Acids Help DCD Kids to Behave  www.NutraIngredients.com, May 3, 2005   Supplementation with fatty acids may be a safe and effective way of dealing with educational and behavioral problems among children with developmental coordination disorder (DCD), according to an Oxford University study published in the May issue of Pediatrics. DCD is a condition affecting around five percent of school-aged children and is linked to behavioral and learning difficulties, problems with motor function and psychosocial issues that may continue into adulthood.   According to study authors Alexandra Richardson and Paul Montgomery, both of Oxford University, there is currently no...

Last week, I wrote about a federal agency that most people think is indispensable. In reality, I said, the FDA regulates us to death, literally, by forbidding even dying Americans who can't be helped by established medical treatments from trying innovative therapies. But what's the alternative? Have no oversight? Let any company peddle every dubious medicine to an unsuspecting public? That sounds terrifying. Snake-oil sellers would sell all kinds of harmful stuff. That's why we created the FDA in the first place.

Protandim May Slow Aging Process by Increasing Enzymes That Fight Free Radicals- Dr. Joe McCord's latest research may unravel the mystery of aging. And if he succeeds, the answer could come in the form of a little yellow pill called Protandim. The University of Colorado at Denver biochemistry professor has conducted decades of experiments into a special class of enzymes in the cell that some hope have the potential of extending lives and possibly preventing chronic diseases like cancer, diabetes and heart disease. Much of his work has centered on oxidative stress -- which increases with age. TBARS, which are...

Almost 13 years after the Food and Drug Administration made it easier for companies to speed life-saving medicines to patients, US Representative Edward J. Markey says the system of accelerated drug review is ''broken" and fails to protect patients. Markey, Democrat of Malden, said he came to that conclusion after reviewing documents he requested from the FDA and the Securities and Exchange Commission detailing whether drug companies conducted required clinical trials and reported that information to shareholders. Under legislation he expects to introduce next week, drug companies could face millions of dollars in fines if patients are harmed because tardy...