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Keyword: stemcells

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  • Milestone study probes cancer origin

    08/17/2013 4:54:38 PM PDT · by CutePuppy · 17 replies
    BBC ^ | 2013 August 14 | James Gallagher
    Scientists are reporting a significant milestone for cancer research after charting 21 major mutations behind the vast majority of tumours. The disruptive changes to the genetic code, reported in Nature, accounted for 97% of the 30 most common cancers. Finding out what causes the mutations could lead to new treatments. Some causes, such as smoking are known, but more than half are still a mystery. Cancer Research UK said it was a fascinating and important study. A tumour starts when one of the building blocks of bodies, a cell, goes wrong. Over the course of a lifetime cells pick up...
  • Rethinking 'The Code'

    08/12/2013 11:42:01 PM PDT · by neverdem · 5 replies
    Biology News Net ^ | August 11, 2013 | NA
    A decade ago, gene expression seemed so straightforward: genes were either switched on or off. Not both. Then in 2006, a blockbuster finding reported that developmentally regulated genes in mouse embryonic stem cells can have marks associated with both active and repressed genes, and that such genes, which were referred to as "bivalently marked genes", can be committed to one way or another during development and differentiation. This paradoxical state—akin to figuring out how to navigate a red and green traffic signal—has since undergone scrutiny by labs worldwide. What has been postulated is that the control regions (or promoters) of...
  • Here It Comes … The $375,000 Lab-Grown Beef Burger

    08/04/2013 3:53:18 PM PDT · by neverdem · 31 replies
    ScienceNOW ^ | 2013-08-02 | Kai Kupferschmidt
    Francois Lenoir/Reuters Meet the new meat. Tiny pieces of muscle tissue grown in the lab will make up the patty of the first test-tube burger to be unveiled in London on Monday. If you take some scientists' word for it, the biggest agricultural revolution since the domestication of livestock is starting on Monday—in an arts center in London. At a carefully orchestrated media event, Dutch stem cell researcher Mark Post is planning to present the world's first test-tube hamburger. Its patty is made from meat that Post has laboriously grown from bovine stem cells in his lab at an estimated...
  • Stem Cells in Urine Easy to Isolate and Have Potential for Numerous Therapies

    08/01/2013 6:50:30 AM PDT · by Salman · 21 replies
    Science News ^ | July 31, 2013 | Science News
    Could harvesting stem cells for therapy one day be as simple as asking patients for a urine sample? Researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine and colleagues have identified stem cells in urine that can be directed to become multiple cell types. "These cells can be obtained through a simple, non-invasive low-cost approach that avoids surgical procedures," said Yuanyuan Zhang, M.D., Ph.D., assistant professor of regenerative medicine and senior researcher on the project. Reporting online in the journal Stem Cells, the team successfully directed stem cells from urine to become bladder-type cells, such as smooth muscle...
  • New teeth grown from urine - study

    07/30/2013 10:25:53 AM PDT · by Red Badger · 62 replies
    BBC ^ | 29 July 2013 Last updated at 19:44 ET | By James Gallagher
    Scientists have grown rudimentary teeth out of the most unlikely of sources, human urine. The results, published in Cell Regeneration Journal, showed that urine could be used as a source of stem cells that in turn could be grown into tiny tooth-like structures. The team from China hopes the technique could be developed into a way of replacing lost teeth. Other stem cell researchers caution that that goal faces many challenges. Teams of researchers around the world are looking for ways of growing new teeth to replace those lost with age and poor dental hygiene. Stem cells - the master...
  • Researchers Identify Proteins Key in Stem Cell Production

    07/29/2013 10:02:49 PM PDT · by neverdem · 1 replies
    Sci-News.com ^ | Jul 8, 2013 | Sergio Prostak
    A multinational team of scientists led by Prof Benjamin Blencowe from the University of Toronto has identified proteins that play a key role in controlling pluripotency, which may mean a potential breakthrough in producing the so-called induced pluripotent stem cells.Colonies of the induced pluripotent stem cells (Boston University Center for Regenerative Medicine) Induced pluripotent stem cells can be of great value for medical research because they can flexibly develop into many different types of cells. However, producing these cells is challenging because the proteins that control their generation are largely unknown.The team discovered the proteins using the splicing code developed...
  • The Pro-Life Case for Stem Cell Treatment

    07/11/2010 8:58:58 AM PDT · by Kaslin · 43 replies
    Pajamas Media ^ | July 11, 2010 | Julia Szabo
    A significant percentage of America’s 45.6 million dog owners and 38.2 million cat owners have first-hand familiarity with state-of-the-art medical facilities for pets that rival the most sophisticated human hospitals: animal emergency centers where veterinary specialists — including neurologists, orthopedists, oncologists, and criticalists — prolong the lives of pets whose owners can afford the service. The mainstream media rarely misses a chance to point out that animal medical care in the United States is almost on par with the best in human health care. But the reality is that the level of animal medical innovation has actually surpassed that of...
  • Stricter standards sought to curb stem-cell confusion

    07/23/2013 10:00:26 PM PDT · by neverdem
    Nature News ^ | 23 July 2013 | Helen Shen
    Initiative aims to clarify description of mesenchymal cells. Pamela Robey is used to being sent samples by scientists who are anxious to know whether the mesenchymal stem cells (MSCs) they have extracted from fat can be coaxed to turn into either bone or cartilage. Robey, who directs the Stem Cell Unit at the US National Institutes of Health (NIH), is also used to delivering bad news to many of those who seek her help. “They usually are not happy,” she says, when her attempts to differentiate the cells produce little more than fatty globules. To Robey, that disappointment reflects a...
  • Microparticles create localized control of stem cell differentiation

    07/09/2013 3:12:31 PM PDT · by neverdem · 1 replies
    Phys.org ^ | July 9, 2013 | NA
    Georgia Tech/Emory University Associate Professor Todd McDevitt and graduate student Anh Nguyen make microparticles to be used for delivering growth factors to stem cells. Credit: Rob Felt Before scientists and engineers can realize the dream of using stem cells to create replacements for worn out organs and battle damaged body parts, they'll have to develop ways to grow complex three-dimensional structures in large volumes and at costs that won't bankrupt health care systems. Researchers are now reporting advances in these areas by using gelatin-based microparticles to deliver growth factors to specific areas of embryoid bodies, aggregates of differentiating stem...
  • Synthetic Trachea Recipient Dies

    07/08/2013 6:16:56 PM PDT · by neverdem · 6 replies
    ScienceInsider ^ | 8 July 2013 | Gretchen Vogel
    The youngest patient to receive an artificial trachea seeded with stem cells has died, The New York Times reported today. Hannah Warren, who was born with a rare birth defect that left her without a trachea, underwent surgery in April to have a synthetic trachea implanted that was seeded with stem cells from her bone marrow. She would have turned 3 in August. Her doctors told The New York Times that her death was due to complications related to a second surgery that was needed to repair her esophagus, which had not properly healed after the initial surgery. They said...
  • Alligator Stem Cells Offer Hope for Tooth Regeneration in Humans

    05/18/2013 2:08:28 PM PDT · by LibWhacker · 17 replies
    sci-news.com ^ | 5/17/13 | Natali Anderson
    An international team of scientists led by Prof Cheng-Ming Chuong from the University of Southern California has discovered unique cellular and molecular mechanisms behind tooth renewal in American alligators (Alligator mississippiensis).Their findings, published in the Proceedings of the National Academy of Sciences, pave the way for tooth regeneration in people. “Humans naturally only have two sets of teeth – baby teeth and adult teeth. Ultimately, we want to identify stem cells that can be used as a resource to stimulate tooth renewal in adult humans who have lost teeth. But, to do that, we must first understand how they renew...
  • US researchers make embryonic stem cells from skin [Pro-Abortion Crowd Deeply Saddened]

    05/16/2013 3:32:18 AM PDT · by SoFloFreeper · 5 replies
    France 24 ^ | 5/16/13
    US researchers have reported a breakthrough in stem cell research, describing how they have turned human skin cells into embyronic stem cells for the first time. The method described Wednesday by Oregon State University scientists in the journal Cell, would not likely be able to create human clones, said Shoukhrat Mitalipov, senior scientist at the Oregon National Primate Research Center. But it is an important step in research because it does not require the use of embryos in creating the type of stem cell capable of transforming into any other type of cell in the body.
  • Nineteenth Century Technique Turns Old Mouse Hearts Young

    05/15/2013 2:09:10 PM PDT · by neverdem · 16 replies
    ScienceNOW ^ | 9 May 2013 | Paul Gabrielsen
    Enlarge Image Young at heart. Cross-sections of mouse ventricles show the visible change in size when old hearts are immersed in young blood. Credit: Francesco Loffredo It's time to turn back the clock on an aging ticker. Drawing on an odd experimental technique invented more than a century ago but rarely done now, researchers have found that a blood-borne protein makes old mouse hearts appear young and healthy again. It's not clear yet whether humans would react the same way, but scientists are hopeful that this discovery may help treat one of the heart's most frustrating ailments. "This is probably...
  • Position Yourself for Big Returns in the Stem Cell Space: Jason Kolbert

    05/15/2013 3:34:26 PM PDT · by neverdem · 2 replies
    The Life Sciences Report ^ | May 13th, 2013 | George S. Mack
    This interview was conducted by George S. Mack of The Life Sciences Report (5/10/13) Stem cell companies have languished long enough in micro-cap territory. The industry is now approaching highly visible phase 2 and phase 3 catalysts that will produce results never before seen in medicine. Managing Director and Senior Biotechnology Analyst Jason Kolbert of the Maxim Group has staked out a select group of nascent cell therapy companies positioned to reap huge gains for investors willing to diversify. In this interview with The Life Sciences Report, Kolbert reflects on the regenerative medicine space following the recent RegenMed Investor Day...
  • Obama Admin Allows Company to Use Aborted Baby Cells for Research

    04/21/2013 6:11:47 PM PDT · by Morgana · 14 replies
    life news ^ | Right to Life of Michigan
    Michigan is in the national news because of a disturbing development in human fetal stem cell experimentation. Neuralstem, Inc. announced that it has received approval from the Food and Drug Administration to expand an amyotrophic lateral sclerosis (Lou Gehrig’s disease) Phase II study to the University of Michigan. The stem cells used in the study come from spinal cord tissue taken from a healthy, 8-week-old aborted baby. Phase I of the trial tested whether human fetal stem cells can safely be injected into the spinal cord. According to Neuralstem, the aim of Phase II is to obtain the maximum tolerated...
  • Mayo Clinic: Cardiopoietic 'Smart' Stem Cells Show Promise in Heart Failure Patients

    04/12/2013 7:05:00 PM PDT · by neverdem · 7 replies
    Mayo Clinic ^ | April 10, 2013 | NA
    First-in-humans study introduces next generation cell therapyROCHESTER, Minn. — Translating a Mayo Clinic stem-cell discovery, an international team has demonstrated that therapy with cardiopoietic (cardiogenically-instructed) or "smart" stem cells can improve heart health for people suffering from heart failure. This is the first application in patients of lineage-guided stem cells for targeted regeneration of a failing organ, paving the way to development of next generation regenerative medicine solutions. Results of the clinical trial appear online of the Journal of the American College of Cardiology. VIDEO ALERT: Audio and video resources are available on the Mayo Clinic News Network. The multi-center,...
  • Discovery in Neuroscience Could Help Re-Wire Appetite Control

    04/06/2013 9:05:01 PM PDT · by neverdem · 10 replies
    ScienceDaily ^ | Apr. 5, 2013 | NA
    Researchers at the University of East Anglia (UEA) have made a discovery in neuroscience that could offer a long-lasting solution to eating disorders such as obesity. It was previously thought that the nerve cells in the brain associated with appetite regulation were generated entirely during an embryo's development in the womb and therefore their numbers were fixed for life. But research published today in the Journal of Neuroscience has identified a population of stem cells capable of generating new appetite-regulating neurons in the brains of young and adult rodents. Obesity has reached epidemic proportions globally. More than 1.4 billion adults...
  • Non-Embryonic Stem Cells: The Dawning of a New Era of Hope

    04/05/2013 9:38:14 AM PDT · by Olog-hai · 2 replies
    Der Spiegel ^ | April 05, 2013 – 04:58 PM | Philip Bethge
    Ethical worries have slowed medical research into applications for stem cells. But scientists like Robert Lanza have developed less controversial ways to derive stem cells from normal body cells rather than embryos and are already launching the first clinical trials. … (T)here is a world premiere in the making: Lanza’s team has cultivated blood platelets that could be tested in hospitals as early as this year. The researcher and his team didn’t harvest the cells from embryonic stem cells, but rather from induced pluripotent stem (iPS) cells derived from normal body cells. …
  • Stem Cells Entering Heart Can Be Tracked With Nano-Hitchhikers

    03/25/2013 10:42:08 PM PDT · by neverdem · 2 replies
    ScienceDaily ^ | Mar. 20, 2013 | NA
    The promise of repairing damaged hearts through regenerative medicine -- infusing stem cells into the heart in the hope that these cells will replace worn out or damaged tissue -- has yet to meet with clinical success. But a highly sensitive visualization technique developed by Stanford University School of Medicine scientists may help speed that promise's realization. The technique is described in a study published March 20 in Science Translational Medicine. Testing the new imaging method in humans is probably three to five years off. Human and animal trials in which stem cells were injected into cardiac tissue to treat...
  • Stem Cell Biology

    03/15/2013 12:37:53 PM PDT · by neverdem · 1 replies
    Cell Research ^ | January 2013 | NA
    The January special issue of Cell Research on Stem Cell Biology brings together the latest reviews and articles in the field. Together with the accompanying web focus, Cell Research delves into our current understanding and investigates recent advances in various aspects of stem cell biology, cell reprogramming, and their relevance to diseases.Special Issue on Stem Cell Biology