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Toddler twin daughters, a husband and countless others are mourning the loss of a woman gone too soon.LayCee Barnett, 28, who had just learned she was expecting another child, felt what her husband Josh Barnett described as flu-like symptoms on Jan. 10. Days later, she got news that shook her world — and then immediately took her from it. "The Wednesday before the 15th, LayCee started getting sick, so we waited a couple of days with things not changing," Josh Barnett recalled. "Fevering started happening and then her legs got really weak, so we went to the Instacare,

Yesterday the Expose published an article which highlighted just a few of the various diseases that were found to be potentially caused by parasites, including cancers. A recent review of nine published research papers by Doctor William Makis further supports the views in the article, but Dr Makis is more qualified to say “it is a reasonable hypothesis that COVID-19 mRNA Vaccine Turbo Cancer patients could benefit significantly from anti-parasitic drugs.” One anti parasitic drug in particular, Fenbendazole, however, has not been sanctioned for human use by the FDA, but despite lacking “official” approval, it is cheap, safe and more...

Researchers at The University of Texas at El Paso have identified a novel pharmaceutical compound that successfully kills leukemia and lymphoma cancer cells, potentially paving the way for new forms of therapy. Renato Aguilera, Ph.D., a professor in the Department of Biological Sciences, is the principal investigator on the project that identified the promising compound, called thiophene F-8. His team's findings were published in the journal PLOS One. "The main goal of my research is to discover new anticancer drugs that can eventually treat distinct cancer types," Aguilera explained. "This research not only had amazing results, it also led to...

Selenium-enriched diets may help ward off myeloid leukemia, and a new study led by researchers has described the mechanism by which this occurs. The findings eventually could help lead to drug therapies that target some types of leukemia—including acute myeloid leukemia (AML), the researchers said. Penn State scientists previously found that supplementing the diets of mice with selenium—a trace mineral naturally found in varying amounts in many foods—stimulated the production of compounds known as cyclopentenone prostaglandins, which appeared to kill or suppress leukemia stem cells. Their latest study shows that these prostaglandins, called CyPGs, bind to and activate a gene,...

Investigators have found that dasatinib, a drug commonly used to treat chronic myeloid leukemia, is strongly associated with kidney injury. The study team strongly believes this study will impact clinical practice significantly, changing standard of care and possibly introducing new black box warnings for dasatinib. Furthermore, the researchers point out that the incidence of kidney injury is a previously unknown severe side effect for this drug. This side effect, they report, is advertised to be rare; however, they observed it in 10% of all participants taking dasatinib. Of concern, they say, is that patients taking dasatinib are currently not screened...

A dying 10-year-old whose last wish was to get married 'tied the knot' with her childhood sweetheart - days before passing away from leukemia. Emma Edwards was diagnosed with acute lymphoblastic leukemia in April last year but parents Alina, 39, and Aaron, 41, said they were hopeful that she'd be able to beat the illness. But in June the family were given the heartbreaking news that Emma's cancer, an aggressive form that affects white blood cells, was incurable and she only had days to live. Emma sadly passed away on July 11. Alina said Emma's dream was to marry boyfriend...

Carter owes the people of Iran an apology. ... Carter's critics always point to his handling of the Iran hostage crisis as the most glaring flaw in his time in office. During the course of that 444-day nightmare, a student mob held 52 U.S. diplomats and civilians hostage, and no amount of negotiation—or attempted military action—could get them released. Thankfully, that sad chapter finally ended on Jan. 20, 1980, the day President Ronald Reagan took the oath of office at the U.S. Capitol. But Carter's true transgression—the original sin that has complicated and shaped U.S. policy in the Middle East...

Anew cancer therapy developed at Jerusalem’s Hadassah-University Medical Center had a 90% response rate in a new clinical trial, with over half of patients going into total remission. The CAR-T therapy — which arms the body’s own immune cells to fight cancer — was able to send multiple myeloma, an extremely deadly cancer that impacts the immune system, into remission. The therapy is the result of years worth of experiments conducted by the hospital’s bone-marrow transplant and immunotherapy department, the Jerusalem Post reported. “We have evidence of a very positive overall response rate with minimal side effects, and they are...

His father, Ken Limper, initially brought his son to urgent care for back pain after Kyle played basketball before taking him to Jefferson Hospital. “They told me in a couple of days, if he doesn’t get better, to bring him back. Well, in a couple of days he couldn’t even stand up,” the grieving dad said. “He couldn’t even get out of bed and I had to help him up and stand him up, then he fell right back down on the bed.” Limper was eventually rushed to St. Christopher’s Hospital for Children, where doctors said the multi-sport athlete’s organs...

A distraught Philadelphia family is living a “nightmare” after their 16-year-old son died within 24 hours of being diagnosed with leukemia. Kyle Limper died peacefully on April 13 from a blood infection caused by the cancer that was discovered that same day, according to his obituary and a report. “Before April 13th, he was a completely healthy and happy young man with no sign of illness,” his obituary states. “It just came and took him in the same day.” His father, Ken Limper, told Fox 29 that he initially brought his son to urgent care for back pain after Kyle...

Consuming a diet rich in vitamin A or its analogs may help prevent children and young adults with acute lymphoblastic leukemia (ALL) reduce their risk of developing painful pancreas inflammation during chemotherapy treatment. For people with ALL, treatment with the enzyme asparaginase helps starve cancer cells by reducing the amount of asparagine circulating in the blood, which the cancer cells need but cannot make themselves. The medication, often used in combination with other chemotherapies, is given via injection into a vein, muscle, or under the skin. However, an estimated 2% to 10% of asparaginase users develop inflammation of the pancreas...

Researchers show the benefits of screening adult patients in remission from acute myeloid leukemia (AML) for residual disease before receiving a bone marrow transplant. About 20,000 adults in the United States are diagnosed each year with AML, a deadly blood cancer, and about one in three live past five years. A bone marrow transplant, which replaces unhealthy blood-forming cells with healthy cells from a donor, often improves these chances. However, research has shown that lingering traces of leukemia can make a transplant less effective. After screening adults with variants commonly associated with AML, researchers showed that the two most common...

Why did the CDC update its page for vinyl chloride nearly two weeks before the Ohio train derailment? The CDC edited its profile for vinyl chloride just recently, removing a section on how the chemical affects children. On February 3, a Norfolk Southern Railroad train derailed in East Palestine, Ohio, emitting toxic clouds into the air and water supplies. The Environmental Protection Agency has deemed the water "safe to drink" – despite the existing reports of wildlife dying in the affected area. Now it seems even the CDC is minimizing the effects of the chemicals involved in the crash, one...

Patients with relapsed or refractory hairy cell leukemia who were treated with vemurafenib experienced excellent response and relapse-free survival, according to a trial. "This finding is important because it represents a targeted and relatively nontoxic and nonchemotherapeutic treatment," said Martin S. Tallman, MD, Hairy cell leukemia (HCL), a rare type of leukemia, manifests when bone marrow produces too many lymphocytes, a type of white blood cell. The disease can be treated with the chemotherapy drug Cladribine either with or without the anti-CD20 monoclonal antibody Rituximab. Unfortunately, 30 to 40 percent of patients will still relapse. In the case of relapsed...

Researchers have found a new method that within hours can predict if certain cancer patients will survive or not after chemotherapy. Acute myeloid leukemia is an aggressive blood cancer with poor survival. Although high rates of initial chemotherapy response, patients often relapse due to the selection and development of chemotherapy-resistant leukemic cells. "When treating patients with leukemia, it is challenging to quickly follow if the patient is responding to therapy or not," says Benedicte Sjo Tislevoll, researcher at the University of Bergen and leader of the new study. The response to therapy is currently measured after weeks to months of...

Progression-free survival is significantly longer with zanubrutinib than ibrutinib among patients with relapsed or refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), according to a study. Jennifer R. Brown, M.D., Ph.D. and colleagues randomly assigned patients with relapsed or refractory CLL or SLL who had undergone one previous course of therapy to receive either zanubrutinib or ibrutinib until disease progression or unacceptable toxic effects. Progression-free survival was assessed to determine whether zanubrutinib was non-inferior to ibrutinib in this final analysis; the superiority of zanubrutinib was assessed if non-inferiority was established. The researchers found that among 652 patients, zanubrutinib...

Leukemia starts in cells that would normally develop into different types of blood cells. Depending on the type of leukemia and the age of the patient, five-year survival rates vary between about 20–80%. A new class of drugs called nuclear exportin inhibitors has recently been approved for use to treat cancers. Nuclear exportins are proteins that shuttle other proteins out of the nucleus of a cell. These new drugs stop the shuttle from leaving the station. "The idea is that if you treat cells with a drug that blocks a nuclear exportin," Wood said, "its client proteins become trapped in...

An inflammatory signaling protein called interleukin-6 has been linked to the progression of acute myeloid leukemia, according to a study. Myelodysplastic syndromes (MDS) are aging-related disorders in which the body produces blood cells ineffectively, which carries the risk of progression to acute myeloid leukemia. While the increased risk of leukemia from MDS has been well-established, the exact mechanisms behind the progression, especially in relationship to aging, have been poorly understood. "We are surprised to find that IL-6, among many other inflammatory signaling proteins, plays an essential role in MDS to AML progression during aging" said Peng Ji, MD, Ph.D., GME....

Researchers have studied the benefit of adding an established drug as a novel targeted therapy in the treatment of acute myeloid leukemia (AML). The results suggest that the drug hydroxyurea can increase treatment efficacy at a relatively low cost. The research could have significant implications for cancer treatment. Acute myeloid leukemia (AML) is an aggressive blood cancer with high mortality. The 5-year relative survival rate after a myeloid leukemia (AML) diagnosis is 30 percent. One reason is that responses to chemotherapy are often insufficient, and a large proportion of patients relapse. SAMHD1, the protein in the leukemia cell, has been...

HIV virions (red) budding and being released from an immune cell (blue). (NIH Image Gallery) AIDS researchers announced on Wednesday that a fourth person has been "cured" of HIV, but the dangerous procedure for patients also battling cancer may be little comfort for the tens of millions living with the virus worldwide. The 66-year-old man, named the "City of Hope" patient after the Californian center where he was treated, was declared in remission in the lead-up to the International AIDS Conference, which begins in Montreal, Canada on Friday. He is the second person to be announced cured this year, after...