Traveled by Native Americans, presidents, generals, gypsies and families seeking a new life in the west, “The Great Road,” known today as Frederick Road or Route 355, provided a path for both the adventurer and the entrepreneur. As the main route northwest from Georgetown, the last port on the Potomac River, it was heavily traveled from the mid 18th century until it was replaced by Interstate 270 in the 1960s. It began as an Indian trail leading from the Piscataway settlement at the mouth of Rock Creek to the great “Conestoga,” a trail that included footpaths and waterways (what we...