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Third Man on Daily PrEP Regimen Contracts HIV
Jezebel ^ | 2/17/17 | Rich Juzwiak

Posted on 04/25/2017 8:12:55 AM PDT by fwdude

In 2012, the FDA approved Truvada as pre-exposure prophylaxis (PrEP) for HIV. An antiretroviral drug used to treat HIV (in combination with other drugs) to the point of suppressing viral loads to undetectable levels in the bloodstream of HIV-positive individuals, Truvada was discovered to be effective in preventing transmission in non-infected individuals if taken everyday. From then until last year (and in the trials that preceded its FDA approval), no known transmissions of HIV had occurred in people who were adhering to a daily PrEP regimen. Many experts warned against deeming the drug 100 percent effective in preventing HIV, but it nonetheless seemed to be the case.

That changed with the announcement in February 2016 that a Canadian man adhering to a daily regimen (per his prescription pill count and a dried-blood spot test that gauges the level of the drug in one’s system) had nonetheless contracted a strain of the virus known to be resistant to emtricitabine and tenofovir, Truvada’s antiretroviral cocktail. A second, similar case of a drug-resistant strain infecting a PrEP-adherent man was made public in October.

And now, there is word of a third case, but this time it’s a bit of a mystery as to how transmission occurred, as the strain contracted by a 50-year-old Dutch man is not known to be resistant to the drugs.

(Excerpt) Read more at jezebel.com ...


TOPICS: Culture/Society; News/Current Events; Philosophy
KEYWORDS: homosexualagenda
Truvada (PrEP) was supposed to be the silver bullet to the HIV/AID epidemic among sexual deviants, but that bullet is quickly losing its punch.

Who could have thunk it?

1 posted on 04/25/2017 8:12:55 AM PDT by fwdude
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To: fwdude

Fair warning, if you read the article, be prepared to confront ungodly high stats for this man on the number of sexual partners he had in a short time. Of course, the Gaystapo will tell us that this doesn’t happen.


2 posted on 04/25/2017 8:14:19 AM PDT by fwdude (Democrats have not been this angry since Republicans freed the slaves.)
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To: fwdude
Truvada was discovered to be effective in preventing transmission in non-infected individuals if taken everyday.

EVERY DAY??!!

Well, I suppose that the taxpayer is footing the bill and that it does cost only about 20 cents a pop... right?

What? "Look it up on Wikipedia," you say?!

In the United States, as of 2016, the wholesale cost is about US $1,415.00 per month.

Oh, my f*king goodness!

Regards,

3 posted on 04/25/2017 8:22:17 AM PDT by alexander_busek (Extraordinary claims require extraordinary evidence.)
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To: fwdude

The wife asked me the other day why we don’t hear as much about deaths from AIDS as we did just a decade or so ago. The reason is groups like ActUp were effective at getting the gummint to subsidize the treatment. Now these drugs are readily available. In my experience, like all drugs, they have side effects that ultimately harm compliance. So the deaths are still occurring but at a lower rate and so media attention has dropped off. HIV is still there, still deadly, but at this point it is an accepted risk. Homosexuals and IV drug users at this point know going in that acting on their desires produces that risk. In the early days of AIDS they had not realized what risks they were taking and so made good victims for the media. Now they are just regarded as foolish by the media and so they realize they have to just accept that risk and not whine.


4 posted on 04/25/2017 8:23:06 AM PDT by wastoute (Government cannot redistribute wealth. Government can only redistribute poverty.)
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To: fwdude

The wages of sin is death even with fancy medicines.


5 posted on 04/25/2017 8:24:34 AM PDT by Rurudyne (Standup Philosopher)
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To: fwdude
Seems to me that a disproportionate amount of treasure is being spent on curing an easily preventable disease.

The government has no problem telling us that steak, bacon, ice cream, hot dogs, coke, candy, etc. are very bad for us, and that we should not eat them. Oh, and they have pronouncements on tobaco too.

Yet when it comes to other "lifestyle" choices like sexual perversion, we wait for the government's pronouncements, but are only left with the sound of chirping crickets.

6 posted on 04/25/2017 9:00:56 AM PDT by Governor Dinwiddie (I don't see a possum.)
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To: wastoute
If you'll notice the recent stats, the official disseminators will shy away from deeming deaths as 'caused by AIDS,' but will simply say something like the patient who died incidentally happened to have AIDS; a convenient way to get around this stark reality.

According to the CDC:
"In 2014, there were 12,333 deaths (due to any cause) of people with diagnosed HIV infection ever classified as AIDS, and 6,721 deaths were attributed directly to HIV."
(https://www.cdc.gov/hiv/statistics/overview/ataglance.html)

How's that for weasel language?

7 posted on 04/25/2017 9:44:25 AM PDT by fwdude (Democrats have not been this angry since Republicans freed the slaves.)
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To: fwdude

There are millions of abstinent people in the world. Those with dangerous and deviant behavior should try it.


8 posted on 04/25/2017 9:48:29 AM PDT by Moonman62 (Make America Great Again!)
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To: Moonman62

Abstinent, or faithful with their naturally opposite sex spouse.

No ‘safe sex’ needed.


9 posted on 04/25/2017 10:57:08 AM PDT by fwdude (Democrats have not been this angry since Republicans freed the slaves.)
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To: fwdude

Not defending folks behavior. But 3 cases out of what are certainly numbers in the 10s of thousands it not much more taking the drug is hardly proof the drug is a failure. Given most of these man tend to have dozens of sex partners a year if not a night, 3 known cases is basically astronomically low transmission rate.

More realistic to basically say that it’s very effective but not 100%


10 posted on 04/25/2017 11:01:42 AM PDT by HamiltonJay
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To: HamiltonJay

Where there are 3, there are likely 30, 300, 3,000. These cases that float to the observable surface are more likely the tip of a much large iceberg.

It’s been found that ideal adherence to the drug regimen is extremely rare. After all, why should we think that those so irresponsible to have so many anonymous sex partners are going to be any more responsible in taking medication?

And imperfect adherence gives way to drug-resistant strains of HIV, which are certain to proliferate in such a promiscuous culture as that of the homosexual male.


11 posted on 04/25/2017 12:41:21 PM PDT by fwdude (Democrats have not been this angry since Republicans freed the slaves.)
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To: alexander_busek

Yep, Obamacare mandates that insurance companies cover what isn’t even an illness, yet. It essentially covers people who WANT to play in sewers from the diseases that sewers carry.

That’s how insane society has become.


12 posted on 04/25/2017 12:48:19 PM PDT by fwdude (Democrats have not been this angry since Republicans freed the slaves.)
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To: wastoute

About a year ago, I read people with HIV died 14 years before their time (70?). I can’t find the original article, but now, they’re printing articles that HIV people live a looooooooong time.


13 posted on 04/25/2017 8:47:18 PM PDT by NetAddicted (Just looking)
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To: fwdude

Attributed directly to HIV?


14 posted on 04/25/2017 8:49:47 PM PDT by NetAddicted (Just looking)
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To: NetAddicted

http://www.aidsmap.com/Life-expectancy-in-HIV-positive-people-in-the-US-still-lags-13-years-behind-HIV-negative-people/page/3040314/


15 posted on 04/25/2017 8:57:01 PM PDT by jjotto ("Ya could look it up!")
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To: jjotto

Thanks, but I KNOW the article said 14 years. I Googled a bunch of other articles that confirmed it.


16 posted on 04/25/2017 9:12:29 PM PDT by NetAddicted (Just looking)
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