All had mothers who were alcoholics when they were pregnant with their children.
While I don't believe they were "born that way" in the sense their DNA or brain was rewired in the womb, I do believe an alcoholic mother is major clue to what causes that particular disorder. Something about the mother besides being prone to alcholism maybe.
As the twig is bent and so on.
The apple rarely falls far from the tree. If the parent is messed up, how can a child growing up in such environment be anything but messed up?